HPLC methods have been developed for the assay of bisacodyl in various pharmaceutical forms. The extraction procedures are simple and the HPLC conditions separate bisacodyl from its degradation products. The chromatography was performed using a Merck LiChrospher RP-select B column, a mobile phase of 55% acetonitrile/45% 0.05 M KH2PO4 and detection by UV at 214 nm.

Submit Manuscript | http://medcraveonline.com Abbreviations: NMR: Nuclear Magnetic Resonance; HPLC: High Performance Liquid Chromatography; RP-HPLC: Reverse Phase High Performance Liquid Chromatography; HPTLC: High Performance Thin Liquid Chromatography; TLC: Thin Liquid Chromatography; API’s: Active Pharmaceutical Ingredient’s; LOD: Limit of Detection; LOQ: Limit of Quantitation; FTIR: Fourier...