The hepatoprotective activity of red grape seed extracts (GSEs) was investigated against ethanol-induced cytotoxicity. In this study, liver slice culture model was used to demonstrate hepatoprotective activity of two GSEs (water and ethanol) in vitro. The hepatoprotective activity was evaluated by measuring the levels of lipid peroxidation, protein carbonyls, lactate dehydrogenase (LDH) leakage...

Background: Infertility is a disease of the reproductive system that inhibits the ability of a couple to have a Baby. Cyclosporine A (CsA) is a powerful immunosuppressant drug most widely used in management of organ transplantation and autoimmune diseases. The drug has adverse side effects such, hirsutism, and gynecomastia. Hawthorn is one of the oldest herbal medicines that are widely used in ...

New developments in the realm of skin rejuvenation such as phytotherapy are at an astounding increasing pace in the cosmeceutical market. Yet, many of these products that are classified as cosmeceuticals are tested less vigorously and do not have to be approved by the Food and Drug Administration to establish efficacy and safety. Thus, as clinicians, we must ask the question, ‘‘Is there science...

The aim of this study was to assess the antibacterial activity of grape vinegar against F. psychrophilum.The antibacterial activity was determined by using agar well diffusion assays. The vinegar was tested against two strains of F.psychrophilum.While the highest inhibition zone diameter of grape vinegar was determined as 60 mm, the lowest was 47mm against to the pathogen. Grape vinegar display...

INTRODUCTION The first grape juice known to be processed in the United States was produced by Dr. Thomas B. Welch, a New Jersey dentist, in 1869 with the newly developed pasteurization process. Assisted by his wife and their 17-year-old son, Charles, he extracted juice from 18 kg (40 lb) of grapes (Vitis labrusca L.). They filtered and bottled the juice and pasteurized it in hot water to kill t...

The goal of this study was to determine the effect of putrescine, added to the culture medium, on the in vitro development of stenospermic grape (Vitis vinifera L) embryos. The cross breedings of Perlón x G.C88552 and Perlón x Argentina were used. 0 (control), 2 and 4 mM of putrescine were added to the immature seed's culture medium. In Perlón x Argentina, 2 mM of putrescine statistically incre...

Grapes are widely known for health benefits due to their antioxidant content. In wine production, grape stems are often discarded, though they has a higher content of antioxidants than the juice. The effectiveness of using an environmentally friendly solvent, ethanol, as a superheated liquid and supercritical fluid to extract antioxidant compounds from grape stems of organically grown Crimson S...

The increased application of MS technologies to nutrition and cancer prevention research has enabled unique insights into the health benefits of polyphenols. Polyphenols are phytochemicals that appear to have chemical properties that provide valuable health benefits when ingested. In particular, experiments have suggested that grape seed proanthocyanidins, oligomers of the catechin family of po...

Vitis vinifera, known as the grapevine, is native to southern Europe and Western Asia. Grape seed and skin contain several active components including flavonoids, polyphenols, anthocyanins, proanthocyanidins, procyanidines, and the stilbene derivative resveratrol. Grape seed extract in particular has been reported to possess a broad spectrum of pharmacological and therapeutic effects such as an...

Background: Infertility is a problem that now affects many couples that are causing the disintegration of many families and as a psychological crisis, a lot of stress on couples has been entered. Cyclosporine (CsA), a cyclic undecapeptideof fungal origin, is a powerful immunosuppressive agent that has markedly improved graft survival rates in organ transplantation. The drug has adverse side eff...