Metakaolin (MK) prepared by the calcination of kaolin at 550 °C and fly ash (FA) from combustion black coal in a granulating boiler were used to prepare unfired ceramic bonding systems via alkali activation process. A long-term stability mechanical properties samples similar was observed. The optimal metakaolin ratio, type activator (NaOH or water glass) its concentration evaluated after hydrat...

To demonstrate the potential alternative sources of starch used in tablet formulations, starches from taro (TS) and sweet potato (SPS) tubers were prepared with obtained yields of 11.0 and 9.6%, respectively. Both TS and SPS met USP22-NF17 identification and specifications. Their equilibrium moisture contents and gelatinization temperatures were comparable with those of commercial starch, where...

To forecast a complex and non-linear system, such as a stock market, advanced artificial intelligence algorithms, like neural networks (NNs) and genetic algorithms (GAs) have been proposed as new approaches. However, for the average stock investor, two major disadvantages are argued against these advanced algorithms: (1) the rules generated by NNs and GAs are difficult to apply in investment de...

The nanoparticles for pharmaceutical application are around now for over 35 years, but only few are commercialized. The major hurdle in its effective utilization is lack of basic understanding in nanosuspension solidification techniques. This study evaluates the efficacy of high shear granulation in converting nanosuspension to solid oral dosage form. Nanosuspension was manufactured using a med...

Helicobacter hepaticus expresses a member of the cytolethal distending toxin (CDT) family of bacterial cytotoxins. To investigate the role of CDT in the pathogenesis of H. hepaticus, transposon mutagenesis was used to generate a series of isogenic mutants in and around the cdtABC gene cluster. An H. hepaticus transposon mutant with a disrupted cdtABC coding region no longer produced CDT activit...

Granule breakage is an important rate process in wet granulation that promotes product uniformity and controls size strength. In this work, a model to predict granule proposed experimentally validated. The assumes exponential of the surviving granules, dependent on probability breakage; function powder binder properties, as well operating parameters. Validation experiments were performed with b...