Central reading centers (CRCs) have several crucial roles in the conduct of clinical trials, providing key input during the study design, preparation of the operations manual, as well as site and photographer certification. They provide objective, standardized grading of images from study subjects, which determines study eligibility, and also evaluate lesion features at subsequent study visits....

Theoretical views on morphogen gradients have altered dramatically with the massive arrival of molecular data regarding the establishment of graded concentrations in the embryo, and the finely tuned reading by cells of these concentration levels. I review these new perspectives, and analyze in detail two models, one pertaining to the propagation of activin in Xenopus embryos, the other to the i...

this study seeks to examine how teachers’ educational background (those who have educated in tefl in comparison to those who have educated in literature) may influence their beliefs and attitudes on language learning, teaching and the teaching methods they apply in their classes. on a general basis, depending on teachers’ opinion, learning process might be seen as behavioristic, inductive, inte...

Let $G$ be a group with identity $e$. Let $R$ be a $G$-graded commutative ring with a non-zero identity and $M$ be a graded $R$-module. In this article, we introduce the concept of graded almost semiprime submodules. Also, we investigate some basic properties of graded almost semiprime and graded weakly semiprime submodules and give some characterizations of them.

Purpose This paper examines the pedagogical features of massive open online courses (MOOCs) for language learning–known as MOOCs. The mainstream pedagogy MOOCs typically involves provision short videos and reading materials self-study; discussion forums, mostly peer-to-peer interaction on course content; machine-graded quizzes self-assessment. For learning, which has been conventionally underst...