AIMS Levels of antioxidants such as folic acid and selenium decrease in dams exposed to ethanol during gestation and lactation, affecting their antioxidant status, their reproductive function and consequently the health of their progeny. We will study whether a Se (0.5 p.p.m.) plus folic acid (8 p.p.m.) supplemented diet administered to ethanol-exposed dams and male rats prevents the effects pr...

background: reactive oxygen species (ros)-induced lipidperoxidation can lead to dysfunction of sperm and thereby, infertility may be occurred. so, always there is a balance between amount of ros and anti-oxidant molecules in semen. anti-oxidant enzymes of sperm; superoxide dismutase (sod), glutathione peroxidase (gpx), catalse and zinc and selenium can protect it from destructive effects of ros...

Objectives: We hypothesize that enzymatic antioxidants are significant contributors to antioxidant status in gestational diabetes (GDM) through scavenging of free radicals. Methods: We evaluated total antioxidant activity and the activities of two major physiological antioxidant enzymes: glutathione peroxidase (GPX) and superoxide dismutase (SOD) in peripheral blood of 22 pregnant Kuwaiti women...

BACKGROUND Oxidative stress plays a role in the pathophysiology of several diseases and has been documented as a contributor to disease in both the human and veterinary literature. One at-risk cell is the erythrocyte, however, the role of oxidative stress in anemia in dogs has not been widely investigated. HYPOTHESIS/OBJECTIVE Anemic dogs will have an alteration in the activity of glutathione...

Selenium-enriched Japanese radish sprouts (Se-enriched JRS), in which Se-methylselenocysteine accounted for 80% of Se compounds, inhibited mammary tumorigenesis induced by 7,12-dimethylbenz[a]anthracene in rats. The effects of Se-enriched JRS on the oxidative stress-scavenging enzymes were investigated in rats. F344 female rats were fed test diets, in which Se-enriched JRS was added at 0, 2.4, ...

Since little is known about the effect of selenium on the fatty acid profiles (FAP) of human breast milk, the purpose of this study was to measure the effect of habitual dietary selenium (Se) intake on this profile in plasma and breast milk. Subjects were lactating women from three locations in China where habitual selenium intakes are extremely low (Xichang), adequate (Beijing), or extremely h...

Ghrelin is a regulatory peptide with specific anti-oxidative effects. The aim of this study was to investigate the activity of two antioxidant enzymes includes superoxide dismutase (SOD) and glutathione peroxidase (GPx) in erythrocyte of newly-hatched chicken following in ovo administration of ghrelin. The fertilized eggs were divided into four experimental groups; control G1 (without injection...

Hyperglycemia exerts toxic effects on the pancreatic beta-cells. This study investigated the hypothesis that the common antidiabetic drugs glibenclamide and metformin, in combination with tualang honey, offer additional protection for the pancreas of streptozotocin (STZ)-induced diabetic rats against oxidative stress and damage. Diabetes was induced in male Sprague Dawley rats by a single dose ...

In this work, the effect of finishing diet (pasture- or mixed-diet) on lipid and protein oxidation in beef homogenates was evaluated. Oxidation was chemically induced by ferrous iron and hydrogen peroxide. Lipid and protein oxidation were respectively measured by determining TBA reactive substances (TBA-RS) and protein carbonyl groups (DNPH coupling method). Evaluation of the antioxidant status...