Current cancer therapies can cause significant collateral damage due to a lack of specificity and sensitivity. Therefore, we explored the cell death pathway response to gold nanorod (GNR)-mediated photothermal therapy as a highly specific cancer therapeutic to understand the role of apoptosis and necrosis during intense localized heating. By developing this, we can optimize photothermal therapy...

One-dimensional nanostructures of graphene such as graphene nanoribbons (GNRs) can prove attractive for digital electronics in the form of interband tunneling transistors, as they are capable of high drive currents. Here, we report on the transport properties of p-n junctions formed in GNR field effect transistors (FETs). It is found that the current density in the devices is indeed high; in th...

Among all of the plasmonic noble metal nanoparticles the gold nanorod (GNR) retains a special place. Its elongated shape gives it unique anisotropic optical and physico-chemical properties. Owing to possibility to control the end-cap geometry, the GNR is the most tunable shape in the terms of localized surface plasmon resonance (LSPR) spectral range. Moreover, the possibility to synthesize GNRs...

MOTIVATION Microarray gene expression data has increasingly become the common data source that can provide insights into biological processes at a system-wide level. One of the major problems with microarrays is that a dataset consists of relatively few time points with respect to a large number of genes, which makes the problem of inferring gene regulatory network an ill-posed one. On the othe...

Gold nanoparticles (GNPs) are widely used for biomedical applications due to unique optical properties, established synthesis methods, and biological compatibility. Despite important applications of plasmonic heating in thermal therapy, imaging, and diagnostics, the lack of quantification in heat generation leads to difficulties in comparing the heating capability for new plasmonic nanostructur...

: The effects of uniaxial tensile strain on the ultimate performance of a dual-gated graphene nanoribbon field-effect transistor (GNR-FET) are studied using a fully analytical model based on effective mass approximation and semiclassical ballistic transport. The model incorporates the effects of edge bond relaxation and third nearest neighbor (3NN) interaction. To calculate the performance metr...

Combination cancer treatment has emerged as a critical approach to achieve remarkable anticancer effect. In this study, we prepared a theranostic nanoformulation that allows for photoacoustic imaging as well as combination gene and photothermal therapy. Gold nanorods (GNR) were coated with dipicolyl amine (DPA), which forms stable complexes with Zn2+ cations. The resulting nanoparticles, Zn(II)...

Submitted for the MAR13 Meeting of The American Physical Society Synthesis of Graphene Nanoribbons with Various Widths and Its Application to Thin-Film Transistor KYUNG TAE KIM, WON HO JO, Seoul National University — Although graphene itself is a zero-bandgap semimetal, graphene nanoribbon (GNR) with a width smaller than 10 nm exhibits semiconducting behavior that renders them suitable for acti...

Spatiotemporal mapping of the position and orientation of nano-machinery inside complex and dynamic cellular environments is essential for the detailed understanding of many bio-physical processes. For the genuine observation of such biomolecular dynamics with high signal to noise ratio and reduced disturbance from the labeling probes, reduction in the size of nano-bio labels and simplification...

Submitted for the MAR10 Meeting of The American Physical Society Half-metallic Armchair Graphene Nanoribbon FUMIYUKI ISHII, KEISUKE SAWADA, MINEO SAITO, Kanazawa University — Among a variety of applications of graphenes, spintronics applications are considered to be hopeful. For an example, spin transport has been experimentally observed by using graphene layers [1]. There are two types of shap...