L-Cysteinesulfinate, a quantitatively important catabolite of L-cysteine, is a substrate of both cysteinesulfinate decarboxylase and glutamate-oxaloacetate transaminase. The former enzyme initiates a pathway leading to taurine; the latter enzyme forms /3-sulfinylpyruvate, which spontaneously decomposes to pyruvate and SOZ. In the present studies, the in uiuo partitioning of cysteinesulfinate be...

Zinc oxide (ZnO) nanoparticles have received growing attention for several biomedical applications. Nanoparticles proposed for these applications possess the potential to interact with biological components such as the blood, cells/ tissues following their administration into the body. Hence we carried out in vivo investigations in Swiss Albino Mice to understand the interaction of ZnO nanorods...

The aim of this study was to investigate the effects of ethanolic extract of the whole plant of Phyllanthus rheedii wight P.rheedii as antihyperglycemic, antihyperlipidemic and antioxidant effect in streptozotocin (STZ) induced diabetic rats. Male Wistar rats were administered P.rheedii (250 mg/kg) orally for 21 days and blood glucose level was measured weekly. At the end of 21 days, the serum ...

Excessive amounts of extracellular glutamate in brain are excitotoxic and lead to neuronal death. Glutamate pyrovate transamiase (GPT) and glutamate oxaloacetate transaminase (GOT) catalyze transamination of glutamate to alpha ketoglutarate. Because vitamin B6 is essential for the enzymes activities, this study was undertaken to examine the effect of vitamin B6 on age related changes of this en...

In the present investigation, various bioassays were conducted to evaluate alteration in levels of enzymes i.e. alkaline phosphatase, acid glutamate oxaloacetate transaminase, pyruvate transaminase and acetylcholinesterase. For this purpose worker termites treated with sub-lethal doses 40% 80% 24 hrs LD50 latex-based combinatorial formulations observations taken at 4 hours intervals up hours. F...

treatment of diseases with natural remedies is gaining popularity because of its fewer side effects.   a systemic and scientific investigation of aqueous extract of euphorbia tirucalli for its antioxidant and hepatoprotective potential against carbon-tetrachloride-induced hepatic damage in rats was carried out . antioxidant property was assessed by using reducing property, superoxide anion scav...

this study was designed to evaluate the hepatoprotective and antioxidant activity of methanol extract of lippia nodiflora (meln) in acute experimental liver injury induced by paracetamol (750mg/kg, b.w). meln at the doses of 200 and 400mg/kg, p.o was administered for 7 days and biochemical parameters such as serum glutamate oxaloacetate transaminase (sgot), glutamate pyruvate transaminase (sgpt...