نتایج جستجو برای: glucosaminidase
تعداد نتایج: 1100 فیلتر نتایج به سال:
Nagstatin, a new inhibitor of N-acetyl-beta-D-glucosaminidase (NAG-ase) was discovered in the fermentation broth of Streptomyces amakusaensis MG846-fF3. It was purified by chromatography on Dowex 50W, Avicel and Sephadex LH-20 followed by the treatment of active carbon and then isolated as colorless powder. Nagstatin has the molecular formula of C12H17N3O6. It is competitive with the substrate,...
Sir: Nagstatin (1) is a novel A^-acetyl-jft-D-glucosaminidase inhibitor isolated from culture nitrates of Streptomyces amakusaensis, and is structurally a nitrogenous 7V-acetylgalactosamine analog fused with an imidazole ring.1} Recently, we have synthesized de-branched nagstatin analogs having different configurations and functionalities, and then determined the absolute structure of nagstatin...
The gene encoding the major autolysin of Staphylococcus aureus 8325/4 has been cloned, sequenced, and insertionally inactivated. The three-domain, 137,384-Da protein has a C-terminal glucosaminidase active site and is involved in cell separation, generalized cell lysis, and release of wall material at the cell surface. Expression occurs throughout growth and is stimulated by low temperatures an...
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