نتایج جستجو برای: glucocorticoids
تعداد نتایج: 14418 فیلتر نتایج به سال:
Glucocorticoids are very effective inhibitors of both the acute and chronic inflammatory response. In this study the hypothesis that glucocorticoids inhibit an early component of the inflammatory response, neutrophil adhesion to endothelium, by down-regulation of adhesion molecules on neutrophils or endothelium was examined. No effect of dexamethasone on neutrophil adhesion to endothelium or of...
Specific binding of glucocorticoids was studied in the cytoplasmic extracts of mouse mammary tumors induced by mammary tumor virus. The binding protein satisfied all the general criteria of hormone receptors namely a specific high affinity for glucocorticoids (4 X 10mg M for dexamethasone) and limited number of binding sites which were saturated with low hormone concentrations (1 X 1OV M). It i...
BACKGROUND AND OBJECTIVES In primary FSGS, calcineurin inhibitors have primarily been studied in patients deemed resistant to glucocorticoid therapy. Few data are available about their use early in the treatment of FSGS. We sought to estimate the association between choice of therapy and ESRD in primary FSGS. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We used an inception cohort of patient...
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