A 56 year old woman presented to the Voice Clinic with recent history of change in voice quality associated with foreign body sensation in the throat and globus pharyngeus. Patient denied any symptoms of gastro-esophageal reflux, namely heartburn and or regurgitation. She had history of smoking but no history of phonotraumatic behavior. Medical history was negative for any systemic illness. On ...

Introduction. Cholesterol granuloma is a rare benign cystic neoplasm characterised by fibrous capsule, and fluid containing cholesterol crystals, multinucleated giant cells, erythrocytes haemosiderin. granulomas are usually found in diverse parts of the temporal bone, most commonly – petrous apex. Very few cases other organs have been reported, to our knowledge none reported larynx. The main pu...

The Globus Toolkit is an open source software toolkit that has become the de-facto standard for middleware used to build Grid services. Globus XIO is an eXtensible Input/Output library for Globus. It provides a POSIX-like API to swappable I/O implementations – essentially “I/O plugins” for Globus. TCP-XM is a modified TCP engine that supports multicast transmission. We have taken this protocol ...

Globus pharyngeus is a common ENT condition. This paper reviews the current evidence on globus and gives a rational guide to the management of patients with globus. The aetiology of globus is still unclear though most ENT surgeons believe that reflux whether acidic or not plays a significant role. Though proton pump inhibitors are used extensively in practice, there is little evidence to suppor...

The globus pallidus occupies a critical position in the 'indirect' pathway of the basal ganglia and, as such, plays an important role in the modulation of movement. In recent years, the importance of the globus pallidus in the normal and malfunctioned basal ganglia is emerging. However, the function and operation of various transmitter systems in this nucleus are largely unknown. GABA is the ma...

BACKGROUND/AIMS Globus is a foreign body sense in the throat without dysphagia, odynophagia, esophageal motility disorders, or gastroesophageal reflux. The etiology is unclear. Previous studies suggested that increased upper esophageal sphincter pressure, gastroesophageal reflux and hypertonicity of esophageal body were possible etiologies. This study was to quantify the upper esophageal sphinc...

The entopeduncular nucleus is one of the basal ganglia's output nuclei, thereby controlling ganglia information processing. Entopeduncular neurons integrate GABAergic inputs from Striatum and globus pallidus, together with glutamatergic subthalamic nucleus. We show that endocannabinoids dopamine interact to modulate long-term plasticity all these primary afferents Our results suggest interplay ...

We are truly grateful to Dr. Flis and colleagues for sharing their experience treating adult and pediatric patients who have experienced accidental ingestion of wire grill brush bristles. Although we report an additional two adult patients who were treated for the same problem during the past 12 months, none of our patients had bowel perforations by these unassuming and miniscule foreign bodies...