OBJECTIVES Gingival overgrowth is a complication of cyclosporine therapy following organ transplantation. Oral azithromycin is frequently used to treat this complication. This study examined the efficacy of local azithromycin, in the form of toothpaste, against cyclosporine-induced gingival overgrowth. MATERIALS AND METHODS Twenty stable renal transplanted patients (10 men and 10 women) with ...

introduction: one of the most common problems we confront in orthodontic therapy is periodontal diseases. initial factor which causes these diseases is colonization of anaerobic microorganisms in subgingival plaque. technically, local environmental changes related to orthodontic band and brackets may influence the bacterial species in periodontal plaque. however, it seems necessary to assess va...

BACKGROUND Various studies have shown that non-surgical periodontal treatment is correlated with reduction in clinical parameters and plasma levels of inflammatory markers. The aim of this study was to evaluate the effect of long-term weekly supragingival irrigations with aerosolized 0.5% hydrogen peroxide as maintenance therapy followed by non-surgical periodontal treatment on clinical paramet...

OBJECTIVE Bleeding disorders are a very important health problem due to the associated high risk of hemorrhage during dental procedures. The present study aimed to investigate oral manifestations of inherited disorders of platelet function (IDPF). METHODS The study included 20 IDPF patients (mean age: 31.90±10.71 years) and 40 healthy controls (mean age: 31.63±9.07 years). Tooth brushing habi...

BACKGROUND The aim of this study was to evaluate the efficacy and safety of herbal dental cream in comparison to fluoride dental cream. OBJECTIVES Clinical evaluation of a novel herbal dental cream in plaque formation: a double-blind, randomized, controlled clinical trial. METHODS One hundred and two patients with established dental plaque were randomly assigned to either herbal dental grou...

OBJECTIVE To evaluate gingival and calculus status among schoolchildren 12 years of age using a geographic information system and multilevel analysis. METHODS A total of 1 002 schoolchildren were selected from 18 municipal districts by means of cluster sampling, from among 25 public and private schools in Piracicaba, São Paulo, Brazil, in 2005. Examinations were carried out by a single calibr...

BACKGROUND AND AIM: Bacterial plaque is the uppermost element in periodontal diseases. Chlorhexidine (CHX) is one of the utmost influential materials in chemical plaque control and ORTHOKIN is a toothpaste claimed to encompass CHX. Although there are various studies on efficacy of different types of CHX formulation in toothpaste, no literature has focused on the anti-plaque effects of toothpast...

OBJECTIVE To assess the relationship between periodontal treatment needs by elderly Brazilians and contextual as well as individual variables. METHODS A cross-sectional study was carried out to assess the need for clinical periodontal treatment, based on National Oral Health Survey (SB Brasil 2010) data on the presence of dental calculus, shallow (3-5 mm) and deep (≥ 6 mm) periodontal pockets...

The use of topical NSAIDs to complement periodontal therapy could help resolve the inflammatory process and clinical signs of the disease more rapidly. A randomized clinical trial was performed on 59 patients, of whom 33 had chronic periodontitis and 26 were healthy controls. All diseased patients underwent scaling and root planing in one quadrant per week with subgingival application of gel 48...

The effect of chronic alcohol intoxication and smoking on the output of salivary immunoglobulin A (IgA) was studied in 37 volunteers: 17 male smoking patients after chronic alcohol intoxication (AS) and 20 control non-smoking male social drinkers (CNS). The DMFT index (decayed, missing, or filled teeth), gingival index and papilla bleeding index (PBI) were assessed. Concentration of IgA in sali...