Superoxide dismutase, ascorbic acid, glutathione and uric acid levels were decreased and xanthine oxidase, glutathione-s-transferase activities were increased in alcohol treated (2 g/kg body weight, once daily for 30 days) group. However, treatment with ethanolic extract of ginger (100 mg/kg, 200 mg/kg body weight, po, once daily for 30 days) these parameters came to normalcy showing the antiox...

The rhizome of ginger (Zingiber officinale) is employed in Asian traditional medicine to treat mild forms of rheumatoid arthritis and fever. We have profiled ginger constituents for robust effects on proinflammatory signaling and cytokine expression in a validated assay using human whole blood. Independent of the stimulus used (LPS, PMA, anti-CD28 Ab, anti-CD3 Ab, and thapsigargin), ginger cons...

BACKGROUND The aim of the present study was to investigate the effect of ginger and glibenclamide on oxidative stress markers. Oxidative stress is caused by an unbalance between a relative overload of oxidants and depletion of antioxidants, as implicated in the pathogenesis of several chronic diseases, including atherosclerosis and diabetes mellitus. Regarding the role of oxidative stress in th...

PURPOSE/OBJECTIVES To evaluate the effect of ginger as an antiemetic modality for the control of chemotherapy-induced nausea and vomiting (CINV). DATA SOURCES Databases searched included MEDLINE® (PubMed), Embase, CINAHL®, Cochrane Central Register of Controlled Trials, Korean Studies Information Service System, Research Information Sharing Service by the Korean Education and Research Informa...

In the present study, the hypoglycaemic potentials of ginger (Zingiber officinale) were studied in rats (four groups: control, ginger, diabetics and diabetics treated with ginger). Ginger extract was daily orally administered (400 mg/kg,) for 4 weeks to alloxan-induced diabetic rats (150 mg/kg). Fasting blood serum was analysed for blood glucose, insulin, creatinine, blood urea nitrogen, aspart...

Ginger possesses analgesic and pharmacological properties mimicking non-steroidal antiinflammatory drugs. We aimed to determine if ginger supplementation is efficacious for attenuating muscle damage and delayed onset muscle soreness (DOMS) following high-intensity resistance exercise. Following a 5-day supplementation period of placebo or 4 g ginger (randomized groups), 20 non-weight trained pa...

One-day-old cobb-400 broiler chicks (240 nos.) were randomly assigned into four dietary treatments each with three replicates of 20 chicks. Four experimental diets were formulated as control diet (T1) without ginger or garlic, while, birds in group T2, T3 and T4 were fed with diets containing 1 % garlic, 1 % ginger and a combination of 1% of garlic and ginger, respectively. Ginger supplementati...

BACKGROUND The interconnected Ras/ERK and PI3K/AKT pathways play a central role in colorectal tumorigenesis, and they are targets for elucidating mechanisms involved in attempts to induce colon cancer cell death. Both ginger (Zingiber officinale) and honey have been shown to exhibit anti-tumor and anti-inflammation properties against many types of cancer, including colorectal cancer. However, t...

BACKGROUND Some studies reported that ginger was effective in prevention or treatment of post-surgical nausea and vomiting; however, there are controversies. In addition, no study compared the effects of ginger on nausea and vomiting after open and laparoscopic nephrectomies. OBJECTIVES The current study aimed to compare the effect of ginger essence on nausea and vomiting after open versus la...

We describe GINGER, a built system for unconditional, general-purpose, and nearly practical verification of outsourced computation. GINGER is based on PEPPER, which uses the PCP theorem and cryptographic techniques to implement an efficient argument system (a kind of interactive protocol). GINGER slashes query costs via protocol refinements; broadens the computational model to include (primitiv...