يمسج للاتعا نوسينشتاه ايريجورب دروفليج ةمزلاتم دعت يفحق بسانت مدعب فصتي .دللجا ةشاشهل مزلام رطيسم .رويطلا هطقتلا روهظو ،كفلا رغصو ،يننستلا رخأتو ،يهجو ينج يف افون يد ينج ةرفط وه يسيئرلا يثارولا بيعلا نأ امك 16 رمعلا نم غلبي ضيرم ةلاح ريرقتلا اذه فصي .LMNA يذلاو نوسينشتاه ايريجورب دروفليج ضارعأ روهظ عم ماع ضارعأ ترهظ امك .ريبك لكشب تايبدلأا يف ةلالحا فصو تم ةفلتخلما تاصيخشتلا ةشقانم تم امك .ضيرل...

Progeria is characterized by clinical features that mimic premature ageing. Although the mutation responsible for this syndrome has been deciphered, the mechanism of its action remains elusive. Progeria research has gained momentum particularly in the last two decades because of the possibility of revealing evidences about the ageing process in normal and other pathophysiological conditions. Va...

Lamins, the major components of the nuclear lamina, have gained rapidly increasing interest over the past decade as lamin mutations were found to cause numerous devastating diseases. These laminopathies include Emery–Dreifuss muscular dystrophy (EDMD), dilated cardiomyopathy type 1A, limb-girdle muscular dystrophy type 1B, familial partial lipodystrophy (FPLD), Charcot–Marie–Tooth disease type ...

N.J. Ullrich V.M. Silvera S.E. Campbell L.B. Gordon SUMMARY: HGPS is a rare syndrome of segmental premature aging. Our goal was to expand the scope of structural bone and soft-tissue craniofacial abnormalities in HGPS through CT or MR imaging. Using The Progeria Research Foundation Medical and Research Database, 98 imaging studies on 25 patients, birth to 14.1 years of age, were comprehensively...