In this study, we investigated the role of interleukin-6 (IL-6) in Giardia lamblia infections in mice. Elevated IL-6 expression was found in wild-type mice 15 days postinfection. Furthermore, IL-6-deficient mice controlled infections only slowly although normal immunoglobulin A production was observed. Thus, IL-6 is necessary for early control of acute G. lamblia infections.

The presence of normal bacterial flora in the intestinal tract is thought to protect against colonization by pathogens. Only a few specific examples of this protection have been demonstrated for bacterial pathogens and protozoan infections. Mice from one commercial breeding farm were found to be less susceptible to infection with Giardia lamblia than were isogenic mice from another facility. Wh...

      Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases. The life cycle of the organism alternates between the active, proliferating trophozoite and the dormant cyst. 5-Nitroimida-zoles have been used extensively in the treatment of amoebiasis, giardiasis, and trichomoniasis. We have previously synthesized ...

A system of tangential-flow filtration was evaluated for use in the detection of Giardia cysts in drinking water. This method was more sensitive in recovering cysts than a frequently used wound-orlon system of through-filtration.

background: infected with intestinal parasites is one of the most important health and economical problems, which could have different effects, such as diarrheal diseases or death associated. the purpose of this study was to determine the level of prevalence of cryptosporidium and giardia parasites in the vegetable marketed in ilam city. methods: this study was performed on 280 samples of fresh...

Exponential expansion of human populations and human activities within primate habitats has resulted in high potential for pathogen exchange creating challenges for biodiversity conservation and global health. Under such conditions, resilient habitat generalists such as black and gold howler monkeys (Alouatta caraya) may act as effective sentinels to overall ecosystem health and alert us to imp...

Giardiasis is the most common waterborne parasitic infection of the human intestine worldwide. The etiological agent, Giardia duodenalis (syn. G. intestinalis, G. lamblia), is a flagellated, binucleated protozoan parasite which infects a wide range of mammalians [1]. Approximately 280 million people worldwide suffering from symptomatic Giardia infection every year [2]. Giardia is a major cause ...

background : giardia lamblia and helicobacter pylori are two flagellate microorganisms that grow in duodenum and stom­ach. the aim of this study was to evaluate the prevalence of them in patients with dyspepsia and other gi disorders. methods: in this cross-sectional study, co-infection of above-mentioned agents was investigated in a group of 130 patients [me­dian age of 40 yr (range=11-79) inc...

giardia lamblia is one of the most common intestinal protozoan parasites infecting human in the world. the goal of this study was searching for in-vitro effect of folic acid and cobalamin on adhesion and growth of g. lamblia as two important mechanisms in the pathogenesis in tyi-s-33 medium. g. lamblia trophozoites were obtained by in- vitro excystation procedure. three groups of giardia tropho...