Do all disciplines fret over the state of their own intellectual and policy-relevant health? Is it a symptom of our hyper-reflexive and confessional times that collective anxiety has to be rehearsed over the track record, and present and projected performance of a group of scholars? Medical sociology’s lengthy reflections on the state of its own practice are recognizable as part of a more gener...

Research in the area of fetal programming has focused on intrauterine growth restriction. Few studies have attempted to examine programming mechanisms that ultimately lead to lambs with a greater potential for postnatal growth. We previously demonstrated that treatment of ewes with GH at the time of breeding led to an increase in birth weight. Therefore, the objective of this study was to deter...

Growth hormone (GH) plays a pivotal role in the regulation of growth, development and body composition. In order to provide new insights into estrogenic endocrine disruptor (ED) activities in the pituitary gland and the potential role played by estrogen receptors (ERs) in mediating their effects in vivo, we examined GH expression in the pituitary gland of an immature rat model. At postnatal day...

BACKGROUND Learning disability and short stature are cardinal signs of Down's syndrome. Insulin-like growth factor I (IGF-I), regulated by growth hormone (GH) from about 6 months of age, may be involved in brain development. AIMS To study long term effects of GH on linear growth and psychomotor development in young children with Down's syndrome. Study design-Fifteen children with Down's syndr...

organization theory is a discipline on the boundary between economics of organizations, sociology of organizations, management and political science. she is interested in organizations, both commercial and non-commercial, in all their diversity (company, hospital, union, organization, administration, conventions). it analyzes their functioning, structure and development for the purpose of bette...

abstractin this study the main goal is explain the achievements of development after the revolution as a unique and special phenomenon as “various local development” based on the specific realities of iranian society. for this purpose have been used of analytical and concept framework weber’s sociology in explaining the qualitative transformation. according to this model, in creating evolution ...

Background—Learning disability and short stature are cardinal signs of Down’s syndrome. Insulin-like growth factor I (IGF-I), regulated by growth hormone (GH) from about 6 months of age, may be involved in brain development. Aims—To study long term eVects of GH on linear growth and psychomotor development in young children with Down’s syndrome. Study design—Fifteen children with Down’s syndrome...

CONTEXT AND OBJECTIVE A single missense mutation in the GH-1 gene converting codon 77 from arginine (R) to cysteine (C) yields a mutant GH-R77C peptide, which was described as natural GH antagonist. DESIGN, SETTING, AND PATIENTS Heterozygosity for GH-R77C/wt-GH was identified in a Syrian family. The index patient, a boy, was referred for assessment of his short stature (-2.5 SD score) and par...