Binding or potential energy curves have been calculated for the ground-state diatomics H(2)(+), He(2)(+), LiH(+), H(2), N(2), and C(2), for the transition state H(3), and for the triplet first excited state of H(2) using the nonempirical density functionals from the first three rungs of a ladder of approximations: the local spin density (LSD) approximation, the Perdew-Burke-Ernzerhof (PBE) gene...

The ground and lower excited states of Fe2, Fe2(-), and FeO(+) were studied using a number of density functional theory (DFT) methods. Specific attention was paid to the relative state energies, the internuclear distances (re), and the harmonic vibrational frequencies (ωe). A number of factors influencing the calculated values of these properties were examined. These include basis sets, the nat...

We have used density-functional theory generalized gradient approximation GGA to study lithium intercalation at low concentration into anatase TiO2. To describe the defect states produced by Li doping a Hubbard “+U” correction is applied to the Ti d states GGA+U . Uncorrected GGA calculations predict LixTiO2 to be metallic with the excess charge distributed over all Ti sites, whereas GGA+U pred...

Optimal sensor placement OSP technique plays a key role in the structural health monitoring SHM of large-scale structures. Based on the criterion of the OSP for the modal test, an improved genetic algorithm, called “generalized genetic algorithm GGA ”, is adopted to find the optimal placement of sensors. The dual-structure coding method instead of binary coding method is proposed to code the so...

Geranylgeranoic acid (GGA) and 2,3-dihydrogeranylgeranoic acid (2,3-diGGA) are geranylgeraniol-derived metabolites (Kodaira et al. (2002) J Biochem 132: 327-334). In the present study, we examined the effects of these acids on HL-60 cells. The cells were differentiated into neutrophils by GGA stimulation like retinoic acid stimulation. In the case of cells stimulated with 2,3-diGGA, neutrophils...

Avian leukosis is a neoplastic disease caused in part by subgroup J avian leukosis virus J (ALV-J). Micro ribonucleic acids (miRNAs) play pivotal oncogenic and tumour-suppressor roles in tumour development and progression. However, little is known about the potential role of miRNAs in avian leukosis tumours. We have found a novel tumour-suppressor miRNA, gga-miR-375, associated with avian leuko...

Recent experimental studies have shown that the basophil is critical for a subtype of anaphylaxis or IgEmediated very late-phase skin inflammation.1 Motility and activation of basophils are known to be regulated by various endogenous and or exogenous substances. The panel of known such basophil-directed molecules is expanding. One important candidate may be geranylgeranyl compounds, which were ...