Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal hyperproliferation of trophoblastic cells, which derive from the trophectoderm, the outer layer of the blastocyst that would normally develop into the placenta during pregnancy. GTDs encompass hydatidiform mole (HM) (complete and partial), invasive mole, gestational choriocarcinoma, placental-site ...

BACKGROUND Gestational Trophoblastic Disease (GTD) is a heterogeneous group of diseases that includes partial and complete hydatidiform mole, invasive mole, choriocarcinoma and placental site trophoblastic tumour. The incidence of GTD varies in different parts of the world. The malignant potential of this disease is higher in South East Asia in comparison to western countries. Objectives of stu...

BACKGROUND Predictive factors of damage to the Fallopian tube may guide the treatment for patients with tubal pregnancy. The aim of this study was to assess the predictive value of the following parameters: gestational age, serum beta-hCG concentrations and ultrasound findings. METHODS A total of 105 patients with ampullary pregnancy undergoing salpingectomy were analysed. Trophoblastic invas...

Gestational trophoblastic diseases (GTDs) are disorders with abnormal growth of the placenta. They are always associated with a conception.(1) Choriocarcinoma that is a malignant type of GTD, can spread virtually anywhere in the body through hematogenous or lymphatic route, but it most commonly spreads to lung, lower genital tract (cervix, vagina, and vulva), brain, and liver.(2) We report a ca...

Choriocarcinoma is an aggressive trophoblastic neoplasm; its origin could be gestational or non-gestational.  Most are gestational, which means they arise from pregnancy, may abnormal normal. This review includes the published literature about choriocarcinoma's prevalence and risk factors. The researchers searched Science Direct, PubMed, EBSCO, Web of Science, Cochrane library, Scopus....

Gestational trophoblastic disease is a condition of uncertain etiology, comprised of hydatiform mole (complete and partial), invasive mole, choriocarcinoma, and placental site trophoblastic tumor. It arises from abnormal proliferation of trophoblastic tissue. Early diagnosis of gestational trophoblastic disease and its potential complications is important for timely and successful management of...

OBJECTIVE To evaluate the role of surgery in the management of high-risk gestational trophoblastic neoplasia. STUDY DESIGN Twenty-four (48%) of 50 patients treated with etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) regimen as primary or secondary chemotherapy for high-risk gestational trophoblastic neoplasia between 1986 and 2005 underwent 28 adjuvant surgi...

Introduction: Gestational trophoblastic diseases, because of their diverse presentation and the malignant lesions being associated with recurrence, metastasis, mortality, early diagnosis is important help ultrasonogram preoperatively, serial Beta human chorionic gonadotropin, histopathological examination for prompt treatment timely management patients. The study aimed to identify overall preva...

http://dx.doi.org/10.1016/j.ebiom.2016.01.013 2352-3964/Crown Copyright © 2016 Published by Elsevie Gestational trophoblastic diseases (GTD) are a group of disorders that originate from the trophoblast, which is the outer layer of the blastocyst that normally gives rise to the placenta and is the first tissue to differentiate from the developing embryos after implantation. The human chorionic g...