CONTEXT Current screening tests for gestational diabetes mellitus (GDM) are inconvenient. Therefore, alternative screening tests for GDM are desirable. The use of glycohemoglobin A1c (HbA1c) in screening for GDM remains controversial. AIM We undertook this study to evaluate the utility of HbA1c in screening for GDM. SETTINGS AND DESIGN Retrospective study in a tertiary teaching hospital. ...

OBJECTIVE The purpose of this study was to examine associations of weight gain from prepregnancy to glycemic screening with glucose tolerance status. STUDY DESIGN Main outcomes were failed glycemic screening (1-hour glucose result >or= 140 mg/dL) with either 1 high value on 3-hour oral glucose tolerance testing (impaired glucose tolerance in pregnancy) or >or= 2 high values on 3-hour oral glu...

In order to enhance cost-benefit value of the gestational diabetes mellitus screening (GDM) concept universal i.e., all pregnant women for diabetes, has mostly been abandoned in favor selective screening. Selective implies that only with risk factors are being screened GDM. However, some recent studies have shown application approach, GDM may not receive proper and timely diagnosis. This review...

BACKGROUND Gestational diabetes mellitus (GDM) increases the risk for preeclampsia and macrosomia. GDM is conventionally diagnosed by an oral glucose tolerance test (OGTT). Hemoglobin A1c (HbA1c) is a marker for the average glucose level the last 2-3 months. We aimed to study if HbA1c alone or in combination with patient characteristics can be used to screen for GDM and reduce the number of OGT...

OBJECTIVE Both gestational diabetes mellitus (GDM) and mild glucose intolerance in pregnancy identify women at increased risk of future type 2 diabetes. In this context, we queried whether metabolic changes that occur in the 1st year postpartum vary in relation to gestational glucose tolerance status. RESEARCH DESIGN AND METHODS Three-hundred-and-ninety-two women underwent glucose challenge t...

OBJECTIVE To compare the cost and time to diagnosis associated with several screening strategies for diabetes in women with histories of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS We simulated screening for diabetes with fasting plasma glucose (FPG), a 2-h oral glucose tolerance test (OGTT), and A1C annually, every 2 years, and every 3 years over a period of 12 years. We...

The consequences of uncontrolled gestational diabetes is severe to both maternal and fetal well-being. An ideal laboratory test to monitor gestational diabetes should accurately reflect short-term glucose changes. Glycated albumin, by virtue of its short half-life of 14 to 19 days, lends itself as a test to monitor and control gestational diabetes. Analytical approaches for the measurement of g...

background: the efficacy of various screening variables in detection of diabetes mellitus (dm) is unclear.   objective: to determine the efficacy of various diagnostic tests for type 2 dm.   methods: 1021 inhabitants of hakimieh district of tehran aged between 30 and 75 years were studied.  known cases of diabetes and those with factors influencing glucose tolerance test were excluded.  age, se...

Objective The objective of this study is to examine whether a first trimester hemoglobin A1c (A1C) of 5.7 to 6.4% predicts an abnormal second trimester oral glucose tolerance test (OGTT). Methods We conducted a retrospective cohort study of all women screened with A1C through 13 (6/7) weeks' gestation between January 1, 2011, and December 31, 2012. Prediabetic women (A1C of 5.7-6.4%) were compa...

The article by Zhu et al. (1) published inDiabetes Care concludes that a fasting plasma glucose (FPG) at 24–28 weeks’ gestation can be used in lowresource regions as a screening test to identify gestational diabetes mellitus (GDM) in Chinese patients. However, in their experience, a screening protocol using FPG cutoff points of $4.4 and #5.0 mmol/L would fail to identify about 12% of the GDM ca...