AIMS To determine the expression of p53, Rb, and bcl-2 during the cell cycle in stimulated peripheral blood lymphocytes (PBLs) and microwave heated reactive lymphoid tissue sections. METHODS The expression of p53, Rb and bcl-2 proteins in paraffin wax embedded tonsil tissue sections was detected by immunohistochemistry using an (APAAP) technique following microwave irradiation. Flow cytometri...

Background: Teratoma is a tumor comprised of three germinal layers classified as mature or immature in most cases. Most solid teratomas are benign but may turn malignant; therefore, complete resection advised these They usually occur women. Primary rectal infrequent, and only few cases have been described the literature. Teratomas common cystic that rise ovary, testicle, retroperitoneum. can al...

objective: mitochondria is a critical organelle within the cell and has important role in the oocyte development, thus the aim of this study was the comparison of mitochondrial distribution within the mouse oocyte at germinal vesicle (gv), germinal vesicle breakdown (gvbd) and metaphase ii (mii) stages using laser confocal microscopy (lscm). materials and methods: after superovulation of adult...

Recent morphologic and histogenetic studies provide a basis for the classification of testicular and ovarian tumors of germinal, mesenchymal, and sex cord origin. That gonadal tumors in the male and female are identical and homologous' 44 is attributed to totipotentiality of the cellular components that contribute to the formation of the gonad. Seminoma, embryonal carcinoma, teratoma, and chori...

In spite of generally accepted dogma that the total number of follicles and oocytes is established in human ovaries during the fetal period of life rather than forming de novo in adult ovaries, some new evidence in the field challenges this understanding. Several studies have shown that different populations of stem cells, such as germinal stem cells and small round stem cells with diameters of...

The present study was aimed to study the effects of hyperlipidaemia on the histology of various reproductive organs. The chronic oral administration of cholesterol diet (400 mg/kg bodyweight/day for 60 day) induced hyperlipidaemia in male rabbits. It showed severe degeneration in germinal epithelium. Few spermatocytes could be seen, but the number was decreased. The seminiferous tubules were wa...

BACKGROUND The exact pathophysiology of testicular degeneration, following varicocele has not been completely understood yet. OBJECTIVE The current study was designed to determine the effect of varicocele on germinal epithelium (GE) cytoplasmic biohistochmical alterations. MATERIALS AND METHODS To follow-up this study, left varicocele was induced in test groups. Non-varicocelized rats were ...