BACKGROUND The association between primary germ cell tumors of the mediastinum (the space between the lung pleura that contains the heart and other chest viscera) and hematologic malignancies has been described by retrospective analysis of patients treated at individual clinical centers. To better characterize the risk of hematologic disorders in patients with extragonadal germ cell tumors and ...

Water clear cells; they can be seen in many tumors such as germ cell tumors, kidney lymphomas, sarcomas, thymic carcinomas, parathyroid paraganglioma. They may primary or occur a result of metastatic conditions. Therefore, histopathologically differential diagnosis difficult confusing. Clinical findings, radiological findings and histopathological evaluation required for diagnosis. 
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Cancer/Testis (CT) antigens are normally only expressed in germ cells and yet are aberrantly activated in a wide variety of human cancers. Most chromosome X-encoded CT antigens (CT-X) show restricted expression in pre-meiotic germ cells in adult testis, except for the expression of SPANX in post-meiotic germ cells. In the present study, the expression of eight CT-X antigens (MAGE-A, NY-ESO-1, G...

Introduction: Germ cell tumors account for 3.5 % of pediatric and yolk sac are the most common pure malignant germ in children. Testis ovary sites involvement children older than 2 years. Case Presentation: A 20-month-old boy with a complaint limping was described this case report. Abdominal ultrasonography showed 52 × 50 mm solid abdominal mass. pelvic computed tomography scans left paraspinal...