Forest-insect systems frequently show cyclic dynamics which has been of considerable interest to both experimental and theoretical ecologists. One important issue has been the manner in which density-dependence acting on the host population through resource competition influences the likelihood of population cycles. Existing models make contradictory predictions. Here, we explore two models tha...

The so-called island model of protein structural transition holds that hydrophobic interactions are the key to both the folding and function of proteins. Herein, the genesis and statistical mechanical basis of the island model of transitions are reviewed, by presenting the results of simulations of such transitions. Elucidating the physicochemical mechanism of protein structural formation is th...

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2.Was a literature review of academic sources completed? The authors state that: “Our review was not conducted as a formal systematic comprehensive review; rather, we focused on primary and grey literature presenting academic, health practitioner and First Nations viewpoints on the topic” (Methods, page 2). Could the authors provide more information on methodology including what information was...

Alcohol is a commonly used drug that has many important health consequences. To understand its physiological effects and predict drug interactions it is important to understanding alcohol’s pharmacokinetics and the factors that influence it. A brief review of the absorption, distribution, metabolism, and excretion of alcohol is provided. Along with a discussion of important factors that influen...