Genetically engineered mouse models have contributed extensively to the field of cancer research. The ability to manipulate the mouse germline affords numerous approaches toward understanding the complexities of this disease, possibly providing accurate preclinical models for therapeutic and diagnostic advances. This review highlights some of the current strategies for modeling cancer in the mo...

due to ever-increasing global diffusion and related socio-economic implications, the detectionof genetically modified organisms (gmos) is very important. in this study, we design a plasmidcontaining two genes in mutated form as construct-specific (cp4 epsps) and event-specific(pd35s). it is applied for quantitative-competitor (qc) pcr as a simple and reliable method forthe detection of gm food....

Over the past few years, genetically modified organisms (GMO) have gradually become more familiar after numerous reports of problems with GMO safety, such as genetically modified (GM) potatoes disrupting immunity, GM corn inducing tumors, and GM rice being fed to unwitting Chinese children. Every time, these reports cause panic among the population and lead to objections to GMO in various fora....

http://www.efsa.eu.int 1 Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the safety of foods and food ingredients derived from herbicide-tolerant genetically modified maize NK603, for which a request for placing on the market was submitted under Article 4 of the Novel Food Regulation (EC) No 258/97 by Monsanto1 (QUESTION NO EFSA-Q-20...

In October 2006 the Joint Research Centre of the European Commission, namely the Community Reference Laboratory for GM Food and Feed (CRL-GMFF), received samples possibly containing Bt rice as tested by GeneScan with a “Bt 63” construct-specific method. The CRL-GMFF, as a result of the analyses conducted, suggested to the European Network of GMO Laboratories (ENGL) and to the EU enforcement lab...

The aspiration of biology education is to give students tools to apply knowledge learned in the classroom to everyday life. Genetic modification is a real-world biological concept that relies on an in-depth understanding of the molecular behavior of DNA and proteins. This study investigated undergraduate biology students' conceptions of genetically modified organisms (GMOs) when probed with rea...

Due to the involvement of scientific, industrial, commercial and public sectors of society, the complexity of the issues concerning the safety of genetically modified organisms (GMOs) for the environment, agriculture, and human and animal health calls for a wide coverage of information. Accordingly, development of the field of biotechnology, along with concerns related to the fate of released G...

What is negative about negative data? Scientists understand negative data from our training in data analysis and statistics, where we use a positive concept of negative data. Negative data are data that do not enable us to reject our null hypothesis. Such data are often difficult to publish because it is not possible to prove the null hypothesis. Every active research scientist has a large draw...

Two conditions are stated which must be fulfilled in order to safeguard that the negative effects of environmental pollution and risks do not outweigh the beneficial effects of global technological development and free markets. The conditions are: (1) There must be consensus on the conditions under which activities are allowed, among all those who may experience negative effects from those acti...