Copyright © 2016, Infection, Epidemiology and Medicine; Tarbiat Modares University. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. Genetic Determinants Differences between Vibrio chol...

Male field crickets, Gryllus integer, call and attract mates, or they silently intercept females attracted to calling males. Selection experiments demonstrate that the duration of nightly calling has an important genetic component. Mean calling times in high and low lines were significantly different and had realized heritabilities of 0.50 and 0.53, respectively. Selection can operate in such a...

Understanding genetic contributions to individual differences in the capacity for emotional memory has tremendous implications for understanding normal human memory as well as pathological reactions to traumatic stress. Research in the last decade has identified genetic polymorphisms thought to influence cognitive/affective processes that may contribute to emotional memory capacity. In this pap...

AIMS We sought to examine the magnitude of the differences in SNP allele frequencies between five European populations (Scotland, Ireland, Sweden, Bulgaria and Portugal) and to identify the loci with the greatest differences. METHODS We performed a population-based genome-wide association analysis with Affymetrix 6.0 and 5.0 arrays. We used a 4 degrees of freedom χ(2) test to determine the ma...

The C57BL/6 mouse is the most well-known inbred mouse strain, and has been widely used as a genetic background for congenic and mutant mice. A number of C57BL/6 substrains have been derived from the C57BL/6 founder line and are reported to differ in several phenotypes. There are several major sources of C57BL/6 substrains for the biomedical research community. The importance of their genetic an...

Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease. RA likely develops beginning with genetic risk. Investigating of preclinical period of RA will lead to understanding the relationships between genetic and environmental factors. The recent studies confirm the polygenic contribution of the major histocompatibility complex (MHC) to RA. Various genetic factors involve...

Two inbred strains of rats were compared as to their ability to incorporate methionine into surviving liver slices. The strains differed significantly in body weight and their reciprocal cross offspring showed marked heterosis. The J strain was built up from four females and two males of a single litter of the Wayne University Fisher line No. 344, with a pedigree of forty-five generations of si...

An ongoing challenge in biology is to predict the phenotypes of individuals from their genotypes. Genetic variants that cause disease often change an individual's total metabolite profile, or metabolome. In light of our extensive knowledge of metabolic pathways, genetic variants that alter the metabolome may help predict novel phenotypes. To link genetic variants to changes in the metabolome, w...

The remarkable similarity among the genomes of humans and the African great apes could warrant their classification together as a single genus. However, whereas there are many similarities in the biology, life history, and behavior of humans and great apes, there are also many striking differences that need to be explained. The complete sequencing of the human genome creates an opportunity to a...