نتایج جستجو برای: genetic background

تعداد نتایج: 1398542  

Journal: :Japanese Journal of Clinical Immunology 2010

Journal: :Current opinion in structural biology 2010
Tali Gidalevitz Elise A Kikis Richard I Morimoto

The inherently error-prone nature of protein biosynthesis and turnover leads to a constant flux of destabilized proteins. Genetic mutations in conformational disease-associated proteins, as well as exposure to acute and chronic proteotoxic stresses, further increase the load of misfolded protein on the proteostasis network. During aging, this leads to enhanced instability of the proteome, failu...

2014
Adriana Ibarra Tomás Restrepo Winston Rojas Adriana Castillo António Amorim Beatriz Martínez German Burgos Henry Ostos Karen Álvarez Mauricio Camacho Zuleyma Suarez Rui Pereira Leonor Gusmão

The European and African contribution to the pre-existing Native American background has influenced the complex genetic pool of Colombia. Because colonisation was not homogeneous in this country, current populations are, therefore, expected to have different proportions of Native American, European and African ancestral contributions. The aim of this work was to examine 11 urban admixed populat...

Journal: :Evolution; international journal of organic evolution 2002
Jacintha Ellers Carol L Boggs

We investigated the genetic background of intraspecific variation in wing color across an elevational gradient in the butterfly Colias philodice eriphyle. The degree of wing melanization was an accelerating function of elevation, and differences in wing melanization persisted in a common environment. Full-sibling analysis and parent-offspring regression yielded consistent, moderate to high heri...

Journal: :Japanese Journal of Animal Psychology 2012

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