Gas turbines incur a loss of output power during hot seasons due to high ambient air temperatures, and input air cooling systems are often used to partly offset this problem. Here, results are reported for an investigation of the utilization of a heat pump to cool the inlet air of a gas turbine compressor. The analyses are carried out for two climates: the city of Yazd, Iran, which has a hot, a...

BACKGROUND The generation of long-lived memory T cells is critical for successful vaccination but the factors controlling their differentiation are still poorly defined. We tested the hypothesis that the strength of T cell receptor (TCR) signaling contributed to memory CD8(+) T cell generation. METHODOLOGY/PRINCIPAL FINDINGS We manipulated the density of antigenic epitope presented by dendrit...

the aims of surgical treatment for cholesteatoma include complete removal of disease and formation of a dry, self cleaning ear in addition to hearing reconstruction. this presentation concentrates on techniques of open mastoid surgery or modified radical mastoidectomy to achieve a well-constructed cavity. this study analyzes both primary and revision mastoid surgery referred to the author. all ...

To improve our understanding of Rayleigh wave generation and propagation in oceans, the effects of the presence of an island on the Rayleigh wave features are simulated. The analysis of results reveals Rayleigh wave generation in ocean near the island. In the water column, a decrease of amplitude in the vertical component and an increase of amplitude in the radial component of Rayleigh wave wit...

Endoplasmic reticulum (ER)-associated degradation (ERAD) is a protective mechanism against ER stress in which unfolded proteins accumulated in the ER are selectively transported to the cytosol for degradation by the ubiquitin-proteasome system. We cloned the novel ubiquitin ligase HRD1, which is involved in ERAD, and showed that HRD1 promoted amyloid precursor protein (APP) ubiquitination and d...