نتایج جستجو برای: gene signature

تعداد نتایج: 1195406  

2014
Noor Dawany Louise C. Showe Andrew V. Kossenkov Celia Chang Prudence Ive Francesca Conradie Wendy Stevens Ian Sanne Livio Azzoni Luis J. Montaner

BACKGROUND Co-infection with tuberculosis (TB) is the leading cause of death in HIV-infected individuals. However, diagnosis of TB, especially in the presence of an HIV co-infection, can be limiting due to the high inaccuracy associated with the use of conventional diagnostic methods. Here we report a gene signature that can identify a tuberculosis infection in patients co-infected with HIV as ...

Journal: :iranian journal of biotechnology 2013
abolghasem abbasi kajani mohamma reza mofid khalil alami saeid

background: taxol is one of the most important anti-cancer drugs, which is obtained from yew trees (taxus sp.). t+he fist step in side chainassembly of taxol is catalyzed by phenylalanine aminomutase, which converts α-phenylalanine to β-phenylalanine.objectives: in this study, for the fist time, we report on the cloning, preliminary expression and characterization of a full-length gene andcdna ...

Journal: :Carcinogenesis 2007
Jill Everland Larsen Sandra Jane Pavey Linda Hazel Passmore Rayleen Bowman Belinda Edith Clarke Nicholas Kim Hayward Kwun Meng Fong

Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is approximately 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent disease. Conventional prognostic markers are unable to determine which patients with completely resected disease within each stage group are likely to relapse. To identify a gene signature associated...

2015
S ebastien Salas Celine Brulard Philippe Terrier Dominique Ranchere-Vince Agnes Neuville Louis Guillou Marick Lae Agnes Leroux Olivier Verola Sylvie Bonvalot Jean-Yves Blay Axel Le Cesne Alain Aurias Jean-Michel Coindre Frederic Chibon

Purpose: Because desmoid tumors exhibit an unpredictable clinical course, translational research is crucial to identify the predictive factors of progression in addition to the clinical parameters. The main issue is to detect patients who are at a higher risk of progression. The aim of this work was to identify molecular markers that can predict progression-free survival (PFS). Experimental Des...

2018
Shigeo Yamaguchi Shin Takahashi Kaoru Mogushi Yuki Izumi Yumi Nozaki Tadashi Nomizu Yoichiro Kakugawa Takanori Ishida Noriaki Ohuchi Chikashi Ishioka Shunsuke Kato

Purpose TP53 signature has a robust predictive performance for prognosis in early-stage breast cancer, but the experiment that reported this relied on public microarray data and fresh-frozen samples. Before TP53 signature can be used in a clinical setting, a simple and low-cost diagnostic system using formalin-fixed paraffin-embedded (FFPE) samples is needed. New treatments based on the biologi...

Journal: :Bioinformatics 2007
Yijun Sun Steve Goodison Jian Li Li Liu William G. Farmerie

MOTIVATION Accurate prognosis of breast cancer can spare a significant number of breast cancer patients from receiving unnecessary adjuvant systemic treatment and its related expensive medical costs. Recent studies have demonstrated the potential value of gene expression signatures in assessing the risk of post-surgical disease recurrence. However, these studies all attempt to develop genetic m...

Journal: :Breast Cancer Research and Treatment 2017

Journal: :journal of advances in computer research 2013
mohammad mohammadzade alireza ghonodi

the problem of automatic signature recognition has received little attention incomparison with the problem of signature verification, despite its potentialapplications for many business processes and can be used effectively in paperlessoffice projects. this paper presents model-based off-line signature recognition withrotation invariant features. non-linear rotation of signature patterns is one...

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