نتایج جستجو برای: gene expression il 1b
تعداد نتایج: 1705519 فیلتر نتایج به سال:
Terajima, Masanori, Mutsuo Yamaya, Kiyohisa Sekizawa, Shoji Okinaga, Tomoko Suzuki, Norihiro Yamada, Katsutoshi Nakayama, Takashi Ohrui, Takeko Oshima, Yoshio Numazaki, and Hidetada Sasaki. Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1b. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L749–L759, 1997.—Exacerbations of asthma are often associat...
Objective—Intimal growth depends on smooth muscle cell (SMC) migration and proliferation and is regulated by thrombotic and inflammatory responses to vascular injury. Platelet-derived growth factor (PDGF)-BB and interleukin (IL)-1b have been shown to contribute to intimal hyperplasia and lesion progression in atherosclerosis. Mitogenic effects of IL-1 on SMCs have been reported and are attribut...
Background and purpose: Chronic non-healing diabetic wounds are a major medical challenge worldwide. Stem cell therapy has been developed as a new approach in the management of such wounds that need to be explored further. In the present study we aimed to evaluate the effects of adipose derived mesenchymal stem cells (ADSCs) on gene expression level of some important inflammatory factors involv...
Infection with porcine reproductive and respiratory syndrome virus (PRRSV) results in a weak antiviral immune response that leads to a persistent infection in a subset of pigs. We investigated the intensity and timing of the early cytokine responses to PRRSV infection to determine their utility as a predictor of persistence. As part of the ‘‘Big Pig’’ project, we evaluated cytokine gene express...
Background. After long-term treatment with continuous ambulatory peritoneal dialysis (CAPD), some patients may develop peritoneal fibrosis. Peritoneal mesothelial cells (PMCs) participate in the inflammatory reactions in the peritoneal cavity, and transforming growth factor-b1 (TGF-b1) and interleukin-1b (IL-1b) are involved in peritoneal fibrosis. Diltiazem is used frequently in patients with ...
Introduction: High-intensity training increases the expression of anti-inflammatory cytokines and decreases the expression of pre-inflammatory cytokines in healthy individuals. However, there is limited research investigating the role of concurrent training in the expression of these cytokines in diabetics. This study aimed to evaluate the effect of concurrent training on the gene expression of...
The aim of this study was to examine the anti-inflammatory effects of co-administration of growthhormone-releasing peptide-2 (GHRP-2) and growth hormone (GH) on tumor necrosis factor-α (TNF-α),interleukin-6 (IL-6) and inducible nitric oxide synthase (iNOS) gene expression induced by LPS in the mousebrain. Thirty-five male NMRI mice (25±5 g) were injected through the mouse tail vein with saline,...
AIM To evaluate the effects of chronic exposure to ethanol in the liver and the expression of inflammatory genes in zebrafish. METHODS Zebrafish (n = 104), wild type, adult, male and female, were divided into two groups: Control and ethanol (0.05 v/v). The ethanol was directly added into water; tanks water were changed every two days and the ethanol replaced. The animals were fed twice a day ...
OBJECTIVE A great number of studies regarding the associations between IL-1B-511, IL-1B+3954 and IL-1RN VNTR polymorphisms within the IL-1gene cluster and coronary heart disease (CHD) have been published. However, results have been inconsistent. In this study, a meta-analysis was performed to investigate the associations. METHODS Published literature from PubMed and Embase databases were sear...
Introduction Familial Mediterranean fever (FMF) is associated with variations in the MEFV gene resulting in proteolytic activation of IL-1b through the inflammasome complex. There is no established treatment available for those resistant or intolerant to standard of care colchicine treatment. Canakinumab, a fully human selective anti-IL-1b monoclonal antibody with a half-life of ~4-weeks binds ...
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