Background . Prostate cancer is the most common malignant condition among oncological diseases of genitourinary tract, which occupies second place in male mortality from neoplasms. At same time, population patients with prostate heterogeneous: some patients, disease does not require active treatment, while others it progresses rapidly formation metastatic castration-resistant cancer. Therefore,...

background: colibacillosis, caused by different serotypes of avian pathogenic escherichia coli (apec), is one of the important diseases in poultry industry. the isolate o78 is the most prevalent serotype of apec in iran. one of the apec virulence factors, increased serum survival (iss) gene, is related to serum resistance. the usual form of colibacillosis in avian is extraintestinal, and serum ...

duchenne muscular dystrophy (dmd), one of the most common and most severe hereditary muscle diseases, is transmitted as an x-linked recessive trait and is usually fetal before the third decade of life. dmd usually presents between the ages of 2 and 5 with severe, progressive muscle weakness and delayed motor milestones. muscle enzymes in the serum including creatine kinase levels are extremely ...

The induction and regulation of broodiness is of the most important role of prolactin in avian species.The promoter region of the prolactin gene is an appropriate model for studying tissue-specific andhormonally-regulated activation of gene transcription. In this study, the association between prolactinpromoter region alleles and egg production in Fars native chickens was investigated. In total...

The 22q11.2 microdeletion syndrome (22q11.2 DGS) is characterized by an extreme intrafamilial and interfamilial variability. main clinical features are congenital heart defects, palatal abnormalities, learning disability, facial dysmorphisms immune deficiency. In 85–90% of cases, the DGS caused a heterozygous ~3-Mb deletion, including TBX1 gene, considered one major genes responsible for defect...

Abstract Autophagy is an evolutionarily conserved degradation process that degrades damaged proteins to maintain homeostasis and protect cells against stress. In this study, we identified characterized a critical autophagy-related protein, UvAtg14, in Ustilaginoidea virens , which the ortholog of MoAtg14 rice blast fungus Magnaporthe oryzea . UvAtg14 co-localized with UvAtg8 (an autophagy marke...