The purpose of this work is to extend the Geant4-DNA Monte Carlo toolkit include electron interactions with four DNA bases using a set cross sections recently implemented in Geant-DNA CPA100 models and available for liquid water. Electron interaction elastic scattering, ionisation, electronic excitation were calculated adenine, thymine, guanine cytosine. energy range extended relativistic elect...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background: in radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness. metho...

Introduction: The goal of any type of radiation therapy in the treatment of tumors, in addition to destroying cancer cells, is to minimizing radiation to nearby healthy cells and thus reducing side damages. For this purpose, targeted radiation therapy (TRT) is more effective in treating of single cells or small cluster of cells. The main factor in the success of this method is...

Introduction: Radiotherapy plays a vital role in cancer treatment. To establish a new potency in radiosensitize tumor cells, delivery of High-Z materials is offered. To date, several simulation geometries have been applied to define simulation sets. The clustering of nanoparticles (NPs) within the cells is a prominent parameter usually ignored in simulation studies. <stro...

Background: The total yields of direct Single-Strand Breaks (SSBs) and Double-Strand Breaks (DSBs) in proton energies varying from 0.1 to 40 MeV were calculated. While other studies in this field have not used protons with energy less than 0.5 MeV, our results show interesting and complicated behavior of these protons. Materials and Methods: The simulation has been done using the Geant4-DNA too...

The research project BioQuaRT within the European Metrology Research Programme aimed at correlating ion track structure characteristics with the biological effects of radiation and developed measurement and simulation techniques for determining ion track structure on different length scales from about 2 nm to about 10 μm. Within this framework, we investigated methods to translate track-structu...

The effect of 53 MeV proton irradiation on the reliability silicon carbide power MOSFETs was investigated. Post-irradiation gate voltage stress applied and early failures in time-dependent dielectric breakdown (TDDB) test were observed for irradiated devices. drain during affects degradation probability by TDDB tests. Proton-induced single event burnouts (SEB) devices which biased close to thei...

The detector description is an essential component that has to be used to analyse and simulate data resulting from particle collisions in high energy physics experiments. Based on the DD4hep detector description toolkit a flexible and data driven simulation framework was designed using the Geant4 tool-kit. We present this framework and describe the guiding requirements and the architectural des...

We propose an alternative approach for the detection of fast neutrons in energy range from 10-4 to 5 MeV based on 10B-RPCs (hybrid double-gap Resistive Plate Chambers with 10B4C neutron converters) surrounded by a polyethylene moderator. The efficiency as function is obtained Monte Carlo simulations performed Geant4 toolkit several detector configurations. thickness converter optimized maximum ...