rectal cancer is the second most common cancer in large intestine. the prevalence and the number of young patients diagnosed with rectal cancer have made it as one of the major health problems in the world. with regard to the improved access to and use of modern screening tools, a number of new cases are diagnosed each year. considering the location of the rectum and its adjacent organs, manage...

Drug-Loaded Mucoadhesive Patch In article number 2100203, Sukho Park and co-workers demostrate a drug-loaded patch equipped in wireless capsule, which is delivered to the gastrointestinal tract rapidly accurately by an external magnetic field. The has excellent mucoadhesive properties even wet environment. Since nanoparticles doxorubicin are also loaded patch, it generates heat under alternatin...

Introduction This year the subjects that have caught my eye have been some of the major problems in cardiovascular surgery, particularly the epidemic of coronary bypass operations which are now being performed, some of the controversial topics which surround management of patients with breast cancer and a number of interesting papers concerning patients with acute abdominal pain. I must then co...

• SLPI prevents tissue destruction and regulates inflammation at barrier tissues. production function is deregulated in several inflammatory diseases. Excessive expression of cancer cells may promote their metastatic potential. The immune system continuously challenged with large quantities exogenous antigens the barriers between external environment internal human Antimicrobial activity essent...

Microbes release important metabolites that regulate various physiological activities inside and outside of organisms. The human gastrointestinal tract is a reservoir microbes play regulatory roles in modulating the immune system numerous other functions. Thus, there substantial interest these microbial products their clinical significance. These have shown promise as therapies for cancer, infl...

Tumors of the gastrointestinal tract are among the most frequent human malignancies and account for approximately 30% of cancer-related deaths worldwide. Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that control diverse cellular functions such as proliferation, differentiation, and cell death. Owing to their involvement in so many processes, the...

BACKGROUND A cancer registry program has been established in East Azerbaijan and this has emphasized the importance of cancers of gastrointestinal tract in this region. The aim of the present pathology-based cancer registry report is to renew epidemiologic aspects of gastrointestinal tract cancers and estimate recent trends. MATERIALS AND METHODS A survey team reviewed and collected all recor...

BACKGROUND Previous studies have suggested that the immunochemical fecal occult blood test has superior specificity for detecting bleeding in the lower gastrointestinal tract even if bleeding occurs in the upper tract. We conducted a large population-based study involving asymptomatic adults in Taiwan, a population with prevalent upper gastrointestinal lesions, to confirm this claim. METHODS ...