The proposed study is a pre and post treatment study to determine whether commonly used laxative-treatment for clozapine-treated psychiatric inpatients affects gastrointestinal motility (as measured by radiopaque marker (ROM) transit studies). This is a follow up study to the ‘Colonic transit studies to measure gastrointestinal motility in antipsychotic-treated patients’ study described in a pr...

like nausea, vomiting, postprandial fullness, abdominal bloating, abdominal discomfort, heartburn, constipation and diarrhea. It is well known that these symptoms are not always brought about by structural diseases of the gastrointestinal tract. They can, for example, be caused by alterations of gastrointestinal motility and/or sensation. These disorders affect an important percentage of the po...

Constipation is a common and burdensome gastrointestinal disorder that may result from altered gastrointestinal motility. The effect of probiotics on constipation has been increasingly investigated in both animal and human studies, showing promising results. However, there is still uncertainty regarding the mechanisms of action of probiotics on gut motility and constipation. Several factors are...