Skin metastasis is a rare manifestation of internal malignancy. Presence of cutaneous metastasis can be seen in 6.4% of all malignancy at some point in time. Cutaneous metastases as a presentation of upper gastrointestinal malignancy is far less common (<1%). Here we present a case of poorly differentiated adenocarcinoma of the stomach that presented with extensive metastases of skin, liver and...

The study was undertaken to evaluate the role of ultrasound guided fine needle aspiration cytology (FNAC) of gastrointestinal masses in providing higher diagnostic yield and assess its reliability in distinguishing between benign and malignant gastrointestinal lesions. 86 patients with gastrointestinal masses after thorough clinical examination underwent ultrasonographic examination. Those foun...

Cytomegalovirus infection is a common pathogen which rarely cause symptomatic disease in an immunocompetent patient. We present an immocompetent 55 year old male with complaints of pain abdomen and loss of appetite. Upper gastrointestinal endoscopy and radiologic features were suggestive of malignancy and partial gastrectomy was performed. Histopathologic findings were diagnostic of cytomegalov...

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INTRODUCTION Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract. There is an increasing number of literature reports on synchronous occurrence of gastrointestinal stromal tumors and another malignancy of distinct etiology and evolution. The most reported cases include gastric synchronous occurrence of gastrointestinal stromal tumors and adenocar...

Clostridium subterminale (C. subterminale) is a pathogenic species of Clostridium that has been infrequently isolated. We report a case of C. subterminale bacteremia causing sepsis in a patient with metastatic gastrointestinal malignancy.

BACKGROUND Cell-free DNA (cfDNA) extracted from blood has become a clinically feasible biomarker in various types of cancer. However, the clinical significance of cfDNA in gastrointestinal (GI) tract cancer among Asian populations requires further investigation. RESULTS The median cfDNA copy number was highest in esophageal cancer, followed by colorectal cancer and gastric cancer, which were ...

To investigate the effect of remote and proximate cancer on hepatic protein metabolism, we determined rates of total protein synthesis by hepatocytes (HPS) isolated from 31 patients undergoing liver wedge biopsy: 7 patients with benign disease, 14 with gastric cancer, and 10 with colorectal cancer (5 of whom had liver metastases). Patients with malignant disease without weight loss had a threef...

A bezoar is a hard, and solid, foreign body located in the gastrointestinal tract that may recur. Bezoar is classified according to its origin. Pharmacobezoars develop in the gastrointestinal tract due to alterations in anatomical structure and/or intestinal motility. In this paper, a case, not yet defined in the literature, of a pharmacobezoar causing a mechanical obstruction that is accompani...