The aim of the study was to investigate the improving effect of Garcinia cambogia extract on performance metrics, and serum non-esterified fatty acids (NEFA) and C-reactive protein (CRP) levels in rats fed with atherogenic diet. Thirty, one-year-old, female Sprague-Dawley rats were randomly assigned to threeexperimental groups of ten animals each. Control group was fed with basal diet (2% liqui...

The aim of the study was to investigate the preventive effects of dietary Garcinia cambogia extract onlipid metabolism and serum activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST)and gamma-glutamyle transferase (GGT) in rats fed high-lipid diet. Thirty female, one-year-old Sprague-Dawley rats were used and separated into three equal groups. Group 1 (control group) wa...

ETHNOPHARMACOLOGICAL RELEVANCE The stem bark of Garcinia livingstonei is used traditionally as a skin lightening agent. AIM OF THE STUDY To isolate and identify compounds responsible for the observed skin lightening activity of Garcinia livingstonei and to evaluate their cytotoxicity. MATERIALS AND METHODS Constituents of the stem bark and fruits of Garcinia livingstonei were isolated using...

One new benzopyran, nigrolineabenzopyran A (1), two new biphenyls, nigrolineabiphenyls A and B (2, 3), and four new tetraoxygenated xanthones, nigrolineaxanthones T-W (4-7), were isolated from the crude methanol extract of the twigs of Garcinia nigrolineata along with 11 known xanthones. The xanthones isolated from the twigs as well as those from the stem bark were evaluated for antibacterial a...

In this dataset, we distinguish 15 accessions of Garcinia mangostana from Peninsular Malaysia using Fourier transform-infrared spectroscopy coupled with chemometric analysis. We found that the position and intensity of characteristic peaks at 3600-3100 cm(-) (1) in IR spectra allowed discrimination of G. mangostana from different locations. Further principal component analysis (PCA) of all the ...

Five new triterpenes, one 17,14-friedolanostane (garcihombronane F, 1), three 17,13-friedolanostanes (garcihombronanes G-I, 2-4), and one lanostane (garcihombronane J, 5), were isolated from the leaves of Garcinia hombroniana together with nine known compounds including five triterpenes, two ionone-derived glycosides, and two flavonoid glucosides. Their structures were identified by analysis of...

The antimalarial activity of 22 xanthones against chloroquino-resistant strains of Plasmodium falciparum was evaluated. Natural caloxanthone C (1), demethylcalabaxanthone (2), calothwaitesixanthone (3), calozeyloxanthone (4), dombakinaxanthone (5), macluraxanthone (6), and 6-deoxy-gamma-mangostin (7) were isolated from Calophyllum caledonicum. 1,6-dihydroxyxanthone (8), pancixanthone A (9), iso...

Six biflavonoids were isolated from G. madruno, one of which, 7''-O-(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu²⁺, was studied by means of a TBARS assay. The antioxidan...

Twelve xanthones were isolated from the hexane extract of the heartwood of Garcinia mangostana from Myanmar. Their structures were determined using 1D and 2D NMR techniques