We report a patient with multiple endocrine neoplasia type 1 (MEN-1) and an aggressive malignant peripheral nerve sheath tumor (MPNST) arising from a ganglioneuroma of the adrenal gland. Patients with MEN-1 require careful consideration of other tumor associations, including MPNST, as it can portend a poor prognosis. MEN-1 and MPNST have not been reported. We report a patient with multiple endo...

Robert Bagdasaryan, MD  65 year old gentleman underWent screening colonoscopy. A 5 mm polyp has been identified in the distal ascending colon and has been excised. Microscopically, spindle-shaped cells along with a collection of ganglion cells are identified in the sections taken from the polyp. Ganglioneuromas are mature, benign tumors composed of a proliferation of nerve fibers, Schwann cell...

Ganglioneuromas are infrequent neurogenic tumours. They are generally benign and lymphatic or haematogenic metastases are rare. They grow slowly and may secrete hormones. They are usually present in people aged between 10 and 40 years. The most common location is in the posterior mediastinum and the retroperitoneum. They are usually asymptomatic and, when there are symptoms, these depend on the...

Abstract Introduction Ganglioneuroma is a rare benign subtype of peripheral neuroblastic tumor that arises from sympathetic ganglion cells. Fewer than 10% these cases occur in the head and neck are rarely seen pediatric patients. Clinical symptoms treatment dependent on mass location extension. The authors present case recurrent retropharyngeal ganglioneuroma patient. Report case(s) Patient 2-y...

Background. Adrenal collision tumors (ACTs), in which distinct tumors coexist without intermingling in the same adrenal gland, are rare and their actual prevalence is unknown. ACTs commonly consist of adrenal cortical adenoma, pheochromocytoma, or metastatic malignant tumor. Case Report. A 32-year-old woman who had been experiencing gastric discomfort for one month was referred to our hospital ...

Composite tumors containing pheochromocytoma and ganglioneuroma are rare tumors typically arising in the adrenal glands. Very few were reported outside of the adrenals. We present the case of a middle-aged woman with a retroperitoneal mass that was discovered when she complained of local signs of compression and systemic signs of catecholamine hypersecretion. On pathology the mass was composed ...

We report a case of an unsuspected ganglioneuroma of the choroid in a patient with neurofibromatosis type 1. A 5-year-old girl presented from an outside institution with right proptosis and glaucoma since birth. Magnetic resonance imaging was obtained and showed a cavernous sinus mass extending into the right orbit and multiple orbital lesions. Additionally, increased signal in the posterior gl...