نتایج جستجو برای: g6pd levels in newborns

تعداد نتایج: 17023703  

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2009
Shi Pan Cameron J World Christopher J Kovacs Bradford C Berk

OBJECTIVE Glucose 6-phosphate dehydrogenase (G6PD) maintains cellular NADPH levels, which are essential for cellular functions, such as vascular endothelial growth factor (VEGF)-induced angiogenesis. The molecular mechanisms regulating G6PD in angiogenesis are not fully understood. Because tyrosine phosphorylation is a key regulatory pathway for VEGF-mediated endothelial cell (EC) responses, we...

2013
Rajendra Prasad Ritu Rathi Praveen Kumar

Hyperbilirubinemia is the most common problem encountered in terms newborns which is mainly caused by abnormal liver function, hemolysis or genetic defect. Uncongugated bilirubin is produced mainly by the turnover of erythrocytes, after that it is transported by organic anion transporter polypeptide (OATP) to the liver, where uncongugated bilirubin is conjugated by uridine diphosphoglucuronate ...

Journal: :The Plant cell 2012
Silvia Dal Santo Hansjörg Stampfl Julia Krasensky Stefan Kempa Yves Gibon Elena Petutschnig Wilfried Rozhon Alexander Heuck Tim Clausen Claudia Jonak

Diverse stresses such as high salt conditions cause an increase in reactive oxygen species (ROS), necessitating a redox stress response. However, little is known about the signaling pathways that regulate the antioxidant system to counteract oxidative stress. Here, we show that a Glycogen Synthase Kinase3 from Arabidopsis thaliana (ASKα) regulates stress tolerance by activating Glc-6-phosphate ...

2014
Abdullah Ahmed Al-alimi Syed A. Ali Faisal Muti Al-Hassan Fauziah Mohd Idris Sin-Yeang Teow Narazah Mohd Yusoff

BACKGROUND Dengue virus is endemic in peninsular Malaysia. The clinical manifestations vary depending on the incubation period of the virus as well as the immunity of the patients. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is prevalent in Malaysia where the incidence is 3.2%. It has been noted that some G6PD-deficient individuals suffer from more severe clinical presentation of dengue...

Journal: :International journal of molecular medicine 2006
Chun Hay Ko Karen Li Pak Cheung Ng Kwok Pui Fung Chung Leung Li Raymond Pui-On Wong Kit Man Chui Goldie Jia-Shi Gu Edmund Yung Chi Chiu Wang Tai Fai Fok

Glucose-6-phosphate dehydrogenase (G6PD)-deficient subjects are vulnerable to chemical-induced hemolysis if exposed to oxidative agents. Recent studies reported that green tea and its constituents might act as pro-oxidants. Our objective was to investigate effects of tea and its polyphenolic components on the oxidative status of human G6PD-deficient erythrocytes. Erythrocytes of G6PD-deficient ...

Journal: :The Southeast Asian journal of tropical medicine and public health 2003
Szu-Hui Chiang Kuei-Fen Wu Tze-Tze Liu Shu-Jen Wu Kwang-Jen Hsiao

The nationwide neonatal screening of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Taiwan was started on July 1, 1987. The effective collection rate has reached more than 96% of all newborns since 1993 and the overall incidence rate of G6PD deficiency was about 2%. This screening program has 3 screening centers and 18 referral hospitals, distributed around Taiwan including outlying isl...

Journal: :international journal of reproductive biomedicine 0
fatemeh mirzaei tayebeh amiri moghadam peyman arasteh

background: vitamin d deficiency during pregnancy is associated with some adverse pregnancy outcomes but its relationship with fetal growth is unknown. objective: we compared the 25-hydroxy vitamin d levels between mothers and their small for gestational age (sga) newborns with mothers and their appropriate for gestational age (aga) newborns. materials and methods: the study population included...

Journal: :Journal of the Hellenic Veterinary Medical Society 2022

In this study, to reveal the antioxidant potential of goat milk cells, activities glucose-6-phosphate dehydrogenase (G6PD), glutathione peroxidase (GPx) and levels reduced nicotinamide adenine dinucleotide phosphate (NADPH), total (tGSH),malondialdehyde (MDA), vitamin C (Vit C) protein (TP) in cells were determined correlations between these parameters evaluated. Milk samples collected from 19 ...

2016
Misako Taniguchi Nobuko Mori Chizuru Iramina Akira Yasutake

Weanling male Wistar rats were fed on a 10% soybean protein isolate (SPI) diet for 3 weeks with or without supplementing 0.3% sulfur-containing amino acids (SAA; methionine or cystine) to examine relationship between glutathione (GSH) levels and activities of NADPH-producing enzymes, glucose 6-phosphate dehydrogenase (G6PD) and malic enzyme (ME), in the liver. Of rats on the 10% SPI diet, GSH l...

2015
Saúl Gómez-Manzo Jaime Marcial-Quino America Vanoye-Carlo Sergio Enríquez-Flores Ignacio De la Mora-De la Mora Abigail González-Valdez Itzhel García-Torres Víctor Martínez-Rosas Edgar Sierra-Palacios Fernando Lazcano-Pérez Eduardo Rodríguez-Bustamante Roberto Arreguin-Espinosa Christo Z. Christov

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in the world. More than 160 mutations causing the disease have been identified, but only 10% of these variants have been studied at biochemical and biophysical levels. In this study we report on the functional and structural characterization of three naturally occurring variants corresponding to different classes...

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