introduction: numerous studies have demonstrated that kisspeptin, a peptide from the kiss1 gene, plays an important role in regulating the secretion of gonadotropin releasing hormone (gnrh). also, there is some evidence suggesting that kisspeptin can interact with other neuropeptides for the control of the reproductive axis. in the present study, we have investigated the effect of central admin...

nimodipine, an l-type calcium channel blocker, can induce analgesia. however, it is not clear that this analgesic effect is at the level of spinal or supraspinal pain pathway. in addition, it has been reported that the analgesic effect of nifedipine, another l-type calcium channel blocker is related to the hpa axis, but there is no report indicating the role of this axis in the analgesic effect...

the prevalence of mental health disorders continues to rise worldwide, such that it is estimated that 1in 4 individuals will be affected by a mental health disorder at some point in their lifetime. research has found that the most prevalent mental health disorders are depressive disorder. depression is a common condition, particularly within the aging population. the development of depression, ...

Take an n-dimensional manifold M . Endow it with a distribution, by which I mean a smooth linear subbundle D ⊂ TM of its tangent bundle TM . So, for x ∈ M , we have a k-plane Dx ⊂ TxM , and by letting x vary we obtain a smoothly varying family of k-planes on M . Put a smoothly varying family g of inner products on each k-plane. The data (M,D, g) is, by definition, a sub-Riemannian geometry. Tak...

this study was conducted to determine the use of three-dimensional ultrasonography (3du) in ocular imaging of the dog and measuring of its optical axis. 12 healthy mixed-breed dogs including 6 males and 6 females were studied. 3du of the eyes were done using a 5–12 mhz linear trapezoid transducer. 3du of the eyes were evaluated and the normal optical long axis through a line between the cornea ...

In sheep, parturition is initiated by increased fetal hypothalamic-pituitary-adrenal axis (HPAA) activity leading to PGE(2) and PGF(2alpha) production and a rise in the 17beta-estradiol-progesterone (E(2)/P(4)) ratio. Uteroplacental PG production can also increase fetal HPAA activity. Periconceptional maternal undernutrition accelerates fetal HPAA maturation resulting in preterm labor. We deter...