Ligninolytic fungi accomplish the partial degradation of numerous aromatic organopollutants. Their ability to degrade polycyclic aromatic hydrocarbons (PAHs) is particularly interesting because eukaryotes were previously considered to be unable to cleave fused-ring aromatics. Recent results indicate that extracellular peroxidases of these fungi are responsible for the initial oxidation of PAHs....

Plant biomass is the major carbon source for many fungal species. Due to its complex polymeric nature, degradation of this biomass to digestible monomers requires a large range of enzyme activities. With the availability of an increasing number of fungal genomes, new insights into the diversity of fungi with respect to plant biomass degradation have been obtained. Recent progress in this area w...

Fenticonazole shows unique multimodal action against Candida species involving: 1. Inhibition of secretary aspartate protenase (SAP) there by preventing the growth, adherence, and penetration of Candida sp. including N-acetylcysteine leading to clinically significant reduction in the relapse rate (Figure 1). 2. Inhibits fungal cytochrome P450 3A enzyme, lanosine 14α-demethylase responsible for ...

The filamentous fungus A. niger is a widely used strain in a broad range of industrial processes from food to pharmaceutical industry. One of the most intriguing and often uncontrollable characteristics of this filamentous organism is its complex morphology. It ranges from dense spherical pellets to viscous mycelia. Various process parameters and ingredients are known to influence fungal morpho...