Two studies in this issue of Neuron apply in vivo functional imaging techniques to map out and record from mouse extrastriate visual cortex. They find that distinct areas show hallmarks of processing for different types of visual input and provide a promising path forward to investigate how complex image analysis is performed in the mouse visual system.

By combining the photoswitching and localization of individual fluorophores with spectroscopy on the single molecule level, we demonstrate simultaneous multicolor imaging with low crosstalk and down to 15 nm spatial resolution using only two detection color channels. The applicability of the method to biological specimens is demonstrated on mammalian cells. The combination of far-field fluoresc...

Functional imaging (PET and fMRI) has made great advances in our understanding of the neural basis of auditory processing and speech perception. Here we review perceptual and sensory processing aspects of speech and hearing, as revealed by functional imaging studies. A comparison is made of the peaks of activity in the left hemisphere across the different studies discussed, with implications fo...

Physiological studies of speech production have demonstrated that even simple articulation involves a range of specialized motor and cognitive processes and the neural mechanisms responsible for speech reflect this complexity. Recently, a number of functional imaging techniques have contributed to our knowledge of the neuroanatomical and neurophysiological correlates of speech production. These...

cell replacement therapy has provided the basis for future clinical applications to treat central nervous system injury, a common result of car accidents. induced functional motoneurons are an option for replacing the lost motoneurons. adipose derived stem cells (adscs) are an appropriate source of cells for autologous cell therapy with the ability of neural differentiation. in this study, adsc...

abstractneuroimaging allows noninvasive evaluation of the anatomy, physiology, and function of the brain. it is widely used for diagnosis, treatment planning, and treatment evaluation of neurological disorders as well as understanding functions of the brain in health and disease. neuroimaging modalities include x-ray computed tomography (ct), magnetic resonance imaging (mri), single photon emis...

In the decade and a half since Biswal's fortuitous discovery of spontaneous correlations in functional imaging data, the field of functional connectivity (FC) has seen exponential growth resulting in the identification of widely-replicated intrinsic networks and the innovation of novel analytic methods with the promise of diagnostic application. As such a young field undergoing rapid change, we...

Neural activity in cortex is correlated, an observation that has traditionally been attributed to neurons receiving input from a shared and limited presynaptic pool. Recent studies have shown that correlations are also strongly influenced by network fluctuations that operate over a range of spatial and temporal scales, extending in some cases across cortical areas. These fluctuations are sensit...

1Faculty of Science, University of Oradea, 410087 Oradea, Romania 2School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia 3Department of Physics, Royal Adelaide Hospital, Adelaide, SA 5000, Australia 4Medical Radiation Physics Division, Stockholm University and Karolinska Institutet, 171 76 Stockholm, Sweden 5Department of Medical and Health Sciences, Radiation Phys...