نتایج جستجو برای: fs

تعداد نتایج: 11748  

Journal: :Bioinformatics 2015
Lukas Folkman Yuedong Yang Zhixiu Li Bela Stantic Abdul Sattar Matthew E. Mort David N. Cooper Yunlong Liu Yaoqi Zhou

MOTIVATION Frameshifting (FS) indels and nonsense (NS) variants disrupt the protein-coding sequence downstream of the mutation site by changing the reading frame or introducing a premature termination codon, respectively. Despite such drastic changes to the protein sequence, FS indels and NS variants have been discovered in healthy individuals. How to discriminate disease-causing from neutral F...

Journal: :Circulation 2004
Alessandro Cataliotti Guido Boerrigter Lisa C Costello-Boerrigter John A Schirger Toshihiro Tsuruda Denise M Heublein Horng H Chen Lorenzo S Malatino John C Burnett

BACKGROUND The renal actions of brain natriuretic peptide (BNP) in congestive heart failure (CHF) are associated with increased diuresis and natriuresis, preserved glomerular filtration rate (GFR), and lack of activation of the renin-angiotensin-aldosterone system (RAAS). In contrast, diuretic-induced natriuresis may be associated with reduced GFR and RAAS activation. The objective of this stud...

2011
Andreas Klaus Henrike Planert J. J. Johannes Hjorth Joshua D. Berke Gilad Silberberg Jeanette Hellgren Kotaleski

In the striatal microcircuit, fast-spiking (FS) interneurons have an important role in mediating inhibition onto neighboring medium spiny (MS) projection neurons. In this study, we combined computational modeling with in vitro and in vivo electrophysiological measurements to investigate FS cells in terms of their discharge properties and their synaptic efficacies onto MS neurons. In vivo firing...

2015
C. J. Ravesloot M. F. Van der Schaaf A. M. M. Muijtjens C. Haaring C. L. J. J. Kruitwagen F. J. A. Beek J. Bakker J. P. J. Van Schaik Th. J. Ten Cate

Formula scoring (FS) is the use of a don't know option (DKO) with subtraction of points for wrong answers. Its effect on construct validity and reliability of progress test scores, is subject of discussion. Choosing a DKO may not only be affected by knowledge level, but also by risk taking tendency, and may thus introduce construct-irrelevant variance into the knowledge measurement. On the othe...

Journal: :Expert review of vaccines 2013
Nicola Principi Susanna Esposito

Vaccine administration is the second leading cause of febrile seizures (FS). FS occurrence in children is a serious concern because it leads to public apprehension of vaccinations. This review discusses the clinical implications of FS, its potential link to vaccinations and its impact on official recommendations for vaccinations in children. Vaccines such as the pertussis antigen-containing vac...

Journal: :Cell stem cell 2011
James J H Chong Vashe Chandrakanthan Munira Xaymardan Naisana S Asli Joan Li Ishtiaq Ahmed Corey Heffernan Mary K Menon Christopher J Scarlett Amirsalar Rashidianfar Christine Biben Hans Zoellner Emily K Colvin John E Pimanda Andrew V Biankin Bin Zhou William T Pu Owen W J Prall Richard P Harvey

Colony-forming units - fibroblast (CFU-Fs), analogous to those giving rise to bone marrow (BM) mesenchymal stem cells (MSCs), are present in many organs, although the relationship between BM and organ-specific CFU-Fs in homeostasis and tissue repair is unknown. Here we describe a population of adult cardiac-resident CFU-Fs (cCFU-Fs) that occupy a perivascular, adventitial niche and show broad t...

2013
Abigail T Berman Jason Turowski Rosemarie Mick Keith Cengel Nicole Farnese Lisa Basel-Brown Clementina Mesaros Ian Blair James Lawson Melpo Christofidou-Solomidou James Lee Ramesh Rengan

PURPOSE The standard of care in Locally-Advanced Non-Small Cell Lung Cancer (LA-NSCLC) is chemotherapy and radiation; however, Radiation-Induced Lung Injury (RILI), which may be prevented by the anti-inflammatory and anti-oxidant properties of Flaxseed (FS), impedes its maximum benefit. MATERIALS AND METHODS Patients with LA-NSCLC requiring definitive RT were randomized to one FS or control m...

2018
Jung Hye Byeon Gun-Ha Kim Baik-Lin Eun

BACKGROUND AND PURPOSE Febrile seizures (FS) are the most common type of seizure during childhood, reportedly occurring in 2-5% of children aged 6 months to 5 years. However, there are no national data on the prevalence of FS in Korea. This study determined the prevalence, incidence, and recurrence rates of FS in Korean children using national registry data. METHODS The data were collected fr...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2003
Wen-Jun Gao Yun Wang Patricia S Goldman-Rakic

The computations underlying cognitive functions are performed by a diversity of interactions between interneurons and pyramidal neurons that are subject to modulatory influences. Here we have used paired whole-cell recording to study the influence of dopamine on local inhibitory circuits involving fast-spiking (FS) and non-FS cells, respectively. We found that dopamine depressed inhibitory tran...

Journal: :Cancer nursing 2000
G A Brenes E D Paskett

BACKGROUND Although colorectal cancer is the third most common cancer in women, little is known about predictors of adherence to screening. METHODS A randomly selected sample of 202 predominantly low-income and African-American women were interviewed. Knowledge of, attitudes and beliefs about, and practices related to flexible sigmoidoscopy (FS) screening were assessed. RESULTS The majority...

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