BACKGROUND Several studies in Western populations have indicated that metabolic syndrome (MetS) is inferior to the Framingham risk score (FRS) in predicting coronary heart disease (CHD). However there has been no study about the predictability of MetS vs. FRS for CHD in Korea. METHODS Among the 43,145 persons from the third Korea National Health and Nutrition Examination Survey in 2005, labor...

Exposure to house dust is a significant source of exposure to flame retardant chemicals (FRs), particularly in the US. Given the high exposure there is a need to understand the bioaccessibility of FRs from dust. In this study, Tenax beads (TA) encapsulated within a stainless steel insert were used as an adsorption sink to estimate the dynamic absorption of a suite of FRs commonly detected in in...

Background: The heightened cardiovascular risk associated with metabolic syndrome (MetS) has been documented by several researchers. The Framingham risk score (FRS) provides a simple and efficient method for identifying individuals at cardiovascular risk. The objective was to describe the prevalence of MetS and its association with FRS in predicting cardiovascular disease among a cohort of semi...

An FRS helps in the reservation of facilities (such as tutorial rooms, hotel rooms, lecture theaters) and specific equipment. Different organizations such as academic institutions, hotels, hospitals and companies, have different physical facilities and arrangements for their reservation. Most often, users (individuals or organizations) manage their own reservations with an FRS (e.g., add, delet...

BACKGROUND & OBJECTIVES Metabolic syndrome (MS) is an important determinant of cardiovascular (CV) risk. Framingham Risk Scores (FRS) often underestimate the CV risk in Asians, younger patients and those with MS. Asians often develop coronary artery disease (CAD) at a younger age and also have a high prevalence of MS. Only limited data are available on the relationship between MS and FRS in suc...

BACKGROUND Chronic kidney disease (CKD) is generally considered an independent risk factor for cardiovascular disease (CVD) development, but rates in individuals with estimated glomerular filtration rate (eGFR) >60 ml/min/1.73 m(2) are uncertain. The Framingham global CVD risk score (FRS) equation is a widely accepted tool used to predict CVD risk in the general population. The purpose of the p...

Endocrine disrupting chemicals (EDCs) constitute a major public health concern because they can induce large spectrum of adverse effects by interfering with the hormonal system. Rapid identification potential EDCs using in vitro screenings is therefore critical, particularly for emerging concerns such as replacement flame retardants (FRs). The review aimed at identifying (1) data gaps and resea...

Fibroblast growth factor receptor 1 (Fgfr1) plays pleiotropic roles during embryonic development, but the mechanisms by which this receptor signals in vivo have not previously been elucidated. Biochemical studies have implicated Fgf receptor-specific substrates (Frs2, Frs3) as the principal mediators of Fgfr1 signal transduction to the MAPK and PI3K pathways. To determine the developmental requ...

Identification of patients with a high probability of developing cardiovascular diseases (CVDs) is important for efficient treatment of type 2 diabetes. Although the Framingham risk score (FRS) is considered a useful tool for quantitative assessment of the risk for CVD in the general populations (1,2), the score does not have sufficient power to predict future onset of CVD in type 2 diabetic pa...

CONTEXT Guidelines advise that all adults undergo coronary heart disease (CHD) risk assessment to guide preventive treatment intensity. Although the Framingham Risk Score (FRS) is often recommended for this, it has been suggested that risk assessment may be improved by additional tests such as coronary artery calcium scoring (CACS). OBJECTIVES To determine whether CACS assessment combined wit...