Synthetic DNA is the linchpin of rapidly accelerating biotechnological era and perhaps most promising candidate for long-term digital data storage. Despite huge advances, manufacturing error-free at low cost high throughput remains challenging. Borrowing from well-established sequencing-by-synthesis technologies, we describe a new solution error correction.

apoptosis, a physiologic mechanism to eliminate unwanted cells, is also induced by ionizing irradiation, through production of free radicals. it has been demonstrated that antioxidants such as vitamin e are able to protect cells from damage caused by free radicals. taken together we found it reasonable to make an attempt to evaluate the protective effect of vitamin e against apoptosis. the irra...

objective: irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. the present study evaluated the effect of lactobacillus plantarum a7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (hepg2) by comet assay. materials and methods: hepg2 were incubated with irinotecan (100 µm), heat-killed cells (0.025 µg/ml) + irinotecan...

Analysis of cell-free DNA (cfDNA) in the blood has shown promise for monitoring a variety biological processes. Plasma cfDNA is mixture comprising molecules released from various bodily tissues, mediated by characteristic fragmentations occurring during cell death. Fragmentation non-random and contains tissue-of-origin information, which been demonstrated circulating fetal, tumoral, transplante...