A new spontaneous mouse mutation named fierce (frc) is deleted for the nuclear receptor Nr2e1 gene (also known as Tlx, mouse homolog of Drosophila tailless). The fierce mutation is genetically and phenotypically similar to Nr2e1 targeted mutations previously studied on segregating genetic backgrounds. However, we have characterized the fierce brain, eye, and behavioural phenotypes on three defi...

Abstract Fibre Reinforced Concrete (FRC) is internationally recognised as a structural material in the fib Model Code 2010 and at national level recently published ABNT standard NBR 16935, which establishes design procedure based on post-cracking parameters. This publication should foster an increase number of applications FRC Brazil next years. In this context, many researchers have investigat...

The use of fire-retardant/resistant coatings (FRC) is an effective and important method to delay the spread fire or protect intact structure against fire. Due high demand for FRC in end-user industries such as construction transportation, how efficiently determine identity has become a critical but difficult task protection investigation. This paper presents application laser-induced breakdown ...

BACKGROUND Rosacea is a common, incurable skin barrier disorder characterized by relapses and remissions. PURPOSE To evaluate the efficacy of Farmaka Rosacea Cream (FRC), a novel topical formulation for rosacea. METHODS This single-center, open-label pilot study comprised a single-dose substudy in 20 healthy subjects and a long-term, repeat-dose substudy in 22 subjects with rosacea. The 2-h...

Introduction: Functional residual capacity (FRC) measurement is now available on new ventilators as an automated procedure. We compared FRC, static thoraco-pulmonary compliance (Crs) and PaO2 evolution in an experimental model of acute respiratory distress syndrome (ARDS) during a reversed, sequential ramp procedure of positive end-expiratory pressure (PEEP) changes to investigate the potential...

BACKGROUND The aim of this study was to evaluate the response of common sized fiber-reinforced composites (FRCs) to different deflections due to bending forces and comparing it with stainless steel (SS) wires. MATERIALS AND METHODS In this experimental study, two FRC groups with 0.75 mm and 1.2 mm diameters (Everstick Ortho, Stick Tech, Finland) and three SS groups with 0.016 × 0.022 inch, 0....

Previous studies have shown conflicting results on the effect of lung volume on the diaphragm compound muscle action potential (CMAP). Consequently, the ability to quantify the oesophageal diaphragm electromyography (EMG) has been questioned. If lung volume changes have little effect on the diaphragm CMAP the accurate measurement of voluntary EMG, as an index of respiratory drive, may be possib...

Background: We measured Functional Residual Capacity (FRC) of the lungs with three methods in healthy volunteers. The three techniques included a CO2 partial rebreathing technique, nitrogen washout technique, and the reference technique for ambulatory patients, body plethysmography. Materials and Methods: After granting consent to an IRB-approved protocol, each of the 20 healthy volunteers part...

The strength and behavior of fiber reinforced concrete (FRC) members subjected to torsion has received little attention in the literature. primary objective including fibers is bridge cracks once they form, doing so, provide some post-cracking resistance otherwise brittle concrete. This accompanying paper that follows present results a comprehensive experimental analytical study aimed at descri...