The purpose of the study was to compare excess relative risk mortality (ERR per 1 Sv) from solid cancers during acute — catastrophic or accidental and occupational, fractionated chronic exposure. Study materials methods. Materials study: maintained database (source database) on nuclear industry workers about 40 countries, based which a pooled analysis data conducted determine integral value ERR...

Background: Increasing the complexity in modern radiotherapy techniques have increased the delivery time lowering consequently the treatment efficacy. Through simulating the delivery time delay encountered in such techniques, its’ effect on two cancer cell lines and the compensating doses given to prevent such effect was investigated. Materials and Methods: F10B16 and 4T1 cancer cell line...

Similar effects on murine haemopoietic compartment of low dose rate single dose and high dose rate fractionated total body irradiation. Summary This study was designed to compare two different modalities of TBI which are currently used in clinical practice. The same dose of 750 cGy was given to CBA mice either in a single dose at a low dose rate (4 cGy min-') (STBI) or in a fractionated regimen...

Purpose: Spatially Fractionated Radiation Therapy (SFRT) is characterized by large differences in peak and valley doses. Preclinical clinical studies suggest that biological mechanisms lead to differential normal tissue tumor response compared uniform irradiation. We hypothesize evaluate effectiveness understand fundamental mechanisms, radiobiological rather than physical dose quantities should...

BACKGROUND Tracking of post-registration head motion is one of the major problems in frameless stereotaxy. Various attempts in detecting and compensating for this phenomenon rely on a fixed reference device rigidly attached to the patient's head. However, most of such reference tools are either based on an invasive fixation technique or have physical limitations which allow mobility of the head...

A forward stimulated Raman scattering (FSRS) diagnostic was developed for the 60 beam Omega laser facility to investigate the propagation of an intense (∼8x10 W/cm), frequency doubled Nd:glass laser beam (≤360 J, 527 nm, 1 ns) through a mm-scale laser-produced plasma. Forward scattered light was measured with spectral, and temporal resolution using a streaked spectrometer and an absolutely cali...

We describe a new technique permitting the mapping of neural connections in the living human brain. The method combines two well established tools of brain research: transcranial magnetic stimulation (TMS) and positron emission tomography (PET). We use TMS to stimulate directly a selected cortical area while simultaneously measuring changes in brain activity, indexed by cerebral blood flow (CBF...

The purpose of these studies was to quantify the effects of radiation given to mouse lungs at intervals up to 6 months after injection of the maximally tolerated dose of cyclophosphamide. In one set of experiments a single i.p. injection of 300 mg/kg of cyclophosphamide was followed at either 1, 3, or 6 months by a range of single doses of gamma-rays delivered to the whole thorax only. In a sec...