Synthesis of isofagomine has been achieved by implementation of aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a key step. The above rearrangement has also been utilized in the synthesis of biologically important polyhydroxylated piperidine frameworks such as isogalactofagomine, ent-isogalactofagomine and their analogues and some other azasugars as glycosidase inhibitors.

The photochemical behaviors of a series of 9-phenanthreneacetamide (PA) derivatives were investigated using UV, fluorescence, and (1)H-NMR spectroscopy in acetonitrile solutions. To apply the electron transfer (ET) action of PA as a detecting moiety of chemosensors, 4'-(9-phenanthreneacetamido)-benzo-15-crown-5 (1) and 3'-methyl-4'-(9-phenanthreneacetamido)-benzo-15-crown-5 (2) were synthesized...

The title compound, C(40)H(40)O(9), is a product of the double crotonic condensation of bis-(2-acetyl-phen-oxy)-3-oxapentane with bis-(2-formyl-phen-oxy)-3,6-dioxaoctane. The title macromolecule includes the 31-crown-7-ether skeletal unit and adopts a saddle-like conformation. The two ethyl-ene fragments have E configurations. The volume of the inter-nal cavity of the macrocycle is approximatel...

Complexes of benzo-15-crown-5 macrocycle with Li+ and Cs+ ions were investigated by 7Li and 133Cs NMr in a number of nonoqueous solutions. The resulting 1:1 complex with Li+ ion was found to be much more stable than that with Cs+ ion. With the exception of pyridine solutions the stabilities of the complexes varied inversely w...

Reaction of [U(TrenTIPS )(PH2 )] (1, TrenTIPS =N(CH2 CH2 NSiPri3 )3 ) with C6 H5 CH2 K and [U(TrenTIPS )(THF)][BPh4 ] (2) afforded a rare diuranium parent phosphinidiide complex [{U(TrenTIPS )}2 (μ-PH)] (3). Treatment of 3 with C6 H5 CH2 K and two equivalents of benzo-15-crown-5 ether (B15C5) gave the diuranium μ-phosphido complex [{U(TrenTIPS )}2 (μ-P)][K(B15C5)2 ] (4). Alternatively, reaction...

Poly- and mononuclear metal complexes of 2,3,11,12-bis[4-(10-aminodecylcarbonyl)]benzo-18- crown-6 (L) and Cu(II); Ni(II); Co(II) and Cr(III) have been synthesized and characterized by standard physico-chemical procedures. In the newly prepared complexes the crown moiety oxygen atoms of the macrocyclic host did not generally interact with metal ions, whereas the two amino groups of the ligand a...

Novel bi-chromophoric naphthalimide derivatives containing benzo-15-crown-5 and N-phenyl-aza-15-crown-5 receptor moieties BNI2 and BNI3 were designed and prepared. Significant Förster resonance energy transfer (FRET) from donor (D) amido-naphthalimide to acceptor (A) amino-naphthalimide chromophores as well as photoinduced electron transfer (PET) between the N-aryl receptor and amido-naphthalim...

We report laser spectroscopic and computational studies of host/guest hydration interactions between functional molecules (hosts) and water (guest) in supersonic jets. The examined hosts include dibenzo-18-crown-6-ether (DB18C6), benzo-18-crown-6-ether (B18C6) and calix[4]arene (C4A). The gaseous complexes between the functional molecular hosts and water are generated under jet-cooled condition...