We explore the use of conditional random fields (CRFs) to automatically extract important metadata from clinical research articles. These metadata fields include formulaic metadata about the authors, extracted from the title page, as well as free text fields concerning the study’s critical parameters, such as longitudinal variables and medical intervention methods, extracted from the body text ...

SUMMARY Frameshift (FS) prediction is important for analysis and biological interpretation of metagenomic sequences. Since a genomic context of a short metagenomic sequence is rarely known, there is not enough data available to estimate parameters of species-specific statistical models of protein-coding and non-coding regions. The challenge of ab initio FS detection is, therefore, two fold: (i)...

Guanine-rich sequences can fold into four-stranded structures of stacked guanine-tetrads, so-called G-quadruplexes (G4). These unique motifs have been extensively studied on the DNA level; however, exploration of the biological roles of G4s at the RNA level is just emerging. Here we show that G4 RNA when introduced within coding regions are capable of stimulating -1 ribosomal frameshifting (-1 ...

Tradition Medicines as the name implies have been a cultural age long healing remedy practiced over the year and improved by casual and unformulated experiments, or in some case are totally forgotten with the passing away of the partition in cases where record have not been kept especially skin and bone related cancers with the use of traditional herbal formula and cultural approaches that need...

It is known that for an IP? set A in (N,+) and a sequence hxnin=1 in N, there exists a sum subsystem hynin=1 of hxnin=1 such that FS(hynin=1) [ FP (hynin=1) ✓ A. Similar types of results have also been proved for central? sets where the sequences have been considered from the class of minimal sequences. In this present work, we shall prove some analogous results for C?-sets for a more general c...

This paper discusses the evolution of documentary culture in early medieval Tuscia by quantitatively examining Latin spelling charter scribes relation to following factors: time, distinction between formulaic and non-formulaic parts document, scribe’s domicile, professional status, document type. The asks what charters tells us about administrative socio-cultural changes production scribal educ...

BACKGROUND The renal Fanconi syndrome (FS) is characterized by renal glucosuria, loss of electrolytes, bicarbonate and lactate, generalized hyperaminoaciduria and low-molecular-weight proteinuria. We studied the urinary low-molecular-weight proteome to identify excreted peptides indicative of a pathogenetic mechanism leading to tubular dysfunction. METHODS We established a urinary proteome pa...