1. Nature has evolved an exquisite system for regulation of leucocyte recruitment at sites of tissue inflammation. Mechanical energy translated to the red and white blood cells transports them from large arteries down to the microcirculation. 2. Neutrophils overcome the drag forces of blood flow by forming selectin and integrin adhesive bonds with the endothelium that coats the vessel wall. Leu...

Connexins form a family of transmembrane proteins that consists of 20 members in humans and 21 members in mice. Six connexins assemble into a connexon that can function as a hemichannel or connexon that can dock to a connexon expressed by a neighbouring cell, thereby forming a gap junction channel. Such intercellular channels synchronize responses in multicellular organisms through direct excha...

Endothelial cells respond to molecular and physical forces in development and vascular homeostasis. Deregulation of endothelial responses to flow-induced shear is believed to contribute to many aspects of cardiovascular diseases including atherosclerosis. However, how molecular signals and shear-mediated physical forces integrate to regulate vascular patterning is poorly understood. Here we sho...

Integrins comprise a large family of cell-cell and cell-matrix adhesion receptors that rapidly modulate their adhesiveness. The arrest of leukocyte integrins on target vascular beds involves instantaneous conformational switches generating shear-resistant adhesions. Structural data suggest that these integrins are maintained in low-affinity conformations and must rapidly undergo conformational ...

Nayak et al have discussed in detail the inertial forces such as Gravitational, Coriolis-Lense-Thirring and Centrifugal forces in the Kerr-Newman Space-time in the Kerr-Newman Space-time. The main theme of this paper is to study the Gravitational and Centrifugal forces in the NUT-Kerr-Newman Space-time. Keywords—Gravitational Forces, Centrifugal Forces, Nut-KerrNewman, Space time.

and James F. Lutsko Physics Department CP 231 Université Libre de Bruxelles Blvd. du Triomphe, 1050 Brussels, Belgium Abstract Many recent papers have questioned Irving and Kirkwood’s atomistic expression for stress. In Irving and Kirkwood’s approach both interatomic forces and atomic velocities contribute to stress. It is the velocity-dependent part that has been disputed. To help clarify this...

Traditional mobile phones have been used for alerting purposes by utilizing their SMS and cell broadcasting features. They do however not suit for demanding alerting and command purposes, for the observation of special forces, rescue officers and civilians, or for the post-evaluation of the operation. Current 3G and 4G/LTE smartphones can do all this, but the empirical evidence is missing. This...

Ines M. Hübler Department of General Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (Dated: November 28, 2004) Abstract When an isotropic object is accelerated by plane waves, its limiting speed is less or equal to the wave speed. We study the acceleration of anisotropic objects in classical wave-particle systems. We investigate objects with anisotropic mass dis...