Background & objectives: The urban rail transport network is always at risk due to its special conditions. Many cases indicate the existence of threatening and risk factors for human societies in urban rail transportation systems. Therefore, in this study, with the aim of identifying and prioritizing the risks of urban rail transportation networks in order to increase resilience is on the agend...

Here we describe GenePANDA, a novel network-based tool for prioritizing candidate disease genes. GenePANDA assesses whether a gene is likely a candidate disease gene based on its relative distance to known disease genes in a functional association network. A unique feature of GenePANDA is the introduction of adjusted network distance derived by normalizing the raw network distance between two g...

Given the growing number of elderly people and the fact that elderly people are more vulnerable to social harm on the eve of aging, such as loneliness, depression, etc., therefore, it is important to promote their social health indicators as factors influencing social development. The factors affecting social health seem to be the product of various factors interacting. The purpose of this stud...

As the influence of human activities on natural systems continues to expand, there is a growing need to prioritize not only pristine sites for protection, but also degraded sites for restoration. We present an approach for simultaneously prioritizing sites for protection and restoration that considers landscape patterns for a threatened population of grizzly bears (Ursus arctos) in southwestern...

OBJECTIVE To explore a risk factor approach for identifying preventive interventions that require more in-depth economic assessment, including cost-effectiveness analyses. METHODS A three-step approach was employed to: (i) identify the risk factors that contribute most substantially to disability-adjusted life years (DALYs); (ii) re-rank these risk factors based on the availability of effecti...