Studies were carried out to determine the effects of treatment with killed suspensions of Propionibacterium acnes (formerly designated Corynebacterium parvum) on the course of Mycobacterium leprae infection in mice. Systemic (intravenous or intraperitoneal) treatment with P. acnes failed to significantly alter the growth of M. leprae in the mouse footpad. In contrast, injections of P. acnes dir...

New therapeutic alternatives against leishmaniasis remain a priority. The activity of azithromycin against Leishmania (Leishmania) major has been previously demonstrated. Different responses among species of Leishmania make species-specific drug screening necessary. The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis was evaluated in go...

This article proposes a method of enabling users to share the sensation of walking with each other in a virtual environment (VE). Achieving this shared sensation requires physical equipment, with algorithms to control it. As an example of such physical equipment, a new footpad type of locomotion interface (LI), named GaitMaster2, has been developed and physiologically evaluated. An algorithm fo...

background: cutaneous leishmaniasis caused by l. major is an important public health problem in endemic areas. the aim of this study was to explore the therapeutic effect of microwave and or infrared radiation in the treatment of lesion induced in balb/c mice by l. major inoculation. methods: the footpad lesion was induced in balb/c mice by inoculation of l. major promastigotes subcutaneously. ...

Sweat glands in rat footpads contain a neuronal differentiation activity that switches the phenotype of sympathetic neurons from noradrenergic to cholinergic during normal development in vivo. Extracts of developing and adult sweat glands induce changes in neurotransmitter properties in cultured sympathetic neurons that mimic those observed in vivo. We have characterized further the factors pre...

In some dogs there are preganglionic fibers leaving the cervical spinal cord through the ventral roots of the lower cervical nerves. When these fibers are stimulated electrically in the anesthetized dog with skeletal muscle paralysis (induced by decamethonium), the effects are vasoconstriction in the front footpad, cardiac acceleration and augmentation, and a rise in arterial blood pressure.