A new hierarchical method for the simulation of the protein folding process and the de novo prediction of protein three-dimensional structure is proposed. The reduced representation of the protein alpha-carbon backbone employs lattice discretizations of increasing geometrical resolution and a single ball representation of side chain rotamers. In particular, coarser and finer lattice backbone de...

Protein folding should be complex. Proteins organize themselves into specific three-dimensional structures, through a myriad of conformational changes. The classical view of protein folding describes this process as a nearly sequential series of discrete intermediates. In contrast, the energy landscape theory of folding considers folding as the progressive organization of an ensemble of partial...

In the paper the programmable logic array (PLA) topological optimization problem is dealt with using folding techniques. A PLA folding algorithm based on the method of simulated annealing is presented. A simulated-annealing PLA folding algorithm is presented for multiple unconstrained folding. Then, the algorithm is extended to handle constrained folding. In this way, simple folding is consider...

In this paper, we address a method for supporting origami folding process on origami. We focus on a folding operation with a view to understanding the state of origami. We estimate the folding operations by using one camera. The folding operation can be estimated by comparing origami shapes of before and after a folding operation. A silhouette model is introduced to grasp the correspondence of ...

We investigated the impact of hydrodynamic interactions (HI) on protein folding using a coarse-grained model. The extent of the impact of hydrodynamic interactions, whether it accelerates, retards, or has no effect on protein folding, has been controversial. Together with a theoretical framework of the energy landscape theory (ELT) for protein folding that describes the dynamics of the collecti...

In order to investigate deformation history preserved in the calcite twins in the hinterland of Zagros, several samples have been collected from calcschists of the Paleozoic Sargaz complex in the Faryab area, SE Iran. These samples are related to F1-recumbent folding and thrust shear zones. The twin width is about 1 and 3.8 µm (thin-twin regime); the twin strain amounts 5 and 10%; twin intensit...