نتایج جستجو برای: fok1 polymorphism

تعداد نتایج: 107356  

Journal: :Phoenix medical journal 2021

Cytokines are secreted or membrane-bound proteins that act as mediators of intercellular signaling to regulate homeostasis the immune system. They produced by cells innate and adaptive immunity in response microbes tumor antigens. Although there several studies showing IL2-330 gene polymorphism is associated with many types cancer, far we know, a few study investigating association between lung...

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2015
Min A Jhun Howard Hu Joel Schwartz Marc G Weisskopf Linda H Nie David Sparrow Pantel S Vokonas Sung Kyun Park

BACKGROUND Although the association between lead and cardiovascular disease is well established, potential mechanisms are still poorly understood. Calcium metabolism plays a role in lead toxicity and thus, vitamin D receptor (VDR) polymorphisms have been suggested to modulate the association between lead and health outcomes. We investigated effect modification by VDR genetic polymorphisms in th...

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ژورنال: :iranian red crescent medical journal 0
zahra mojtahedi shiraz institute for cancer research, shiraz university of medical sciences, ir iran nasroolah erfani shiraz institute for cancer research, shiraz university of medical sciences, ir iran mahyar malekzadeh shiraz institute for cancer research, shiraz university of medical sciences, ir iran mohammad reza haghshenas shiraz institute for cancer research, shiraz university of medical sciences, ir iran abbas ghaderi shiraz institute for cancer research, shiraz university of medical sciences, ir iran alamtaj samsami dehaghani department of obstetrics and gynecology, shiraz university of medical sciences, ir iran +98-7112303687, samsamia@sums.ac.ir; department of obstetrics and gynecology, shiraz university of medical sciences, ir iran +98-7112303687, samsamia@sums.ac.ir

background the association between her2 ile655val single nucleotide polymorphism and cancer is controversial. objectives the aim of our study was to investigate this polymorphism in patients with ovarian cancer. patients and methods genomic dna was extracted from peripheral blood leukocytes of 107 patients and 130 healthy women. her2 gene polymorphism was assessed by pcr-rflp. results no signif...

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Journal: : 2023

Chloroform accumulation in the body and increase its steady-state concentrations blood of exposed people have been established to be associated with polymorphisms enzyme genes a genotype involved metabolism water disinfection byproducts (A415G EPHX1 gene, C1091T CYP2E1 zero mutations GSTT1 GSTM1 genes) (р < 0.000001). These correlate higher chloroform levels consuming chlorinated drinking wa...

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Journal: :iranian journal of applied animal science 2014
d.s. kale b.r. yadav j. prasad

dna polymorphism within diacylglycerol transferase 2 (dgat2) / monoacyl glycerol transferases 2 (mogat2), leptin and butyrophilin genes were analysed using pcr-sscp in murrah buffalo. the single strand conformation polymorphism (sscp) analysis of amplified gene fragment in exon 5 of mogat2, exon 3 of leptin and intron 1 of butyrophilin gene revealed different patterns. a, b and c showed the fol...

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Journal: Iranian Journal of Basic Medical Sciences 2015
Ahmad Faraz, Sabir Hussain, Tahir Iqbal,

Resistin (RETN), recently found to be relevant to inflammation and inflammatory disorders. We, therefore, aimed to investigate the potential role of RETN gene polymorphism in pathogenesis of acne vulgaris with familial history. We investigated the RETN-420C/G polymorphism in 180 patients with acne vulgaris and 180 healthy individuals in a case-control association analysis. In this study, we als...

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Journal: :Turkish Journal of Hematology 2018

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ژورنال: پژوهش در پزشکی 2013
باباخانی, آذر, بختیاری, سالار, داودیان, الهام, سایه میری, کوروش, ظ،اهرآراء, مطهره, مرتضوی طباطبائی, سید عبدالرضا, ملکی, محمد حسین,

Abstract Background: PGC-1α is involved in the regulation of several metabolic processes and its reduced expression has been observed in early stages of type 2 diabetes, (T2D). Changes in activity of PGC-1α, probably due to its polymorphisms, have extensive effects on metabolic processes in people with T2D. The association of rs2970847 polymorphism of PGC-1α gene with T2D has been investigat...

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Journal: :Pharmacognosy Journal 2023

Introduction: Amiodarone is one of drug with narrow therapeutics index. This medicine was metabolized by CYP3A4 and CYP2C8. The changes in the activity this enzymes CYP2C8 polymorphism will affect effect. study aimed to determine impact on amiodarone responses. Method: review article search PubMed keywords: ‘amiodarone’ ‘polymorphism CYP3A4’ CYP2C8’. Results: We collect 46 references Conclusion...

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Journal: Iranian Journal of Veterinary Research 2007
A. Eslami A. Gholamian H. Galehdari, L. Nabavi

In this report, β-tubulin gene polymorphism was investigated in Haemonchus contortus  populations isolated from sheep flocks in different regions of Khouzestan province, southwestern Iran. The samples were chosen on the basis of regional variation in benzimidazole treatment background of sheep flocks. Our objective was to study the relationship between treatment background andβ -tubulin gene po...

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    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->